955F229A49FE84B10F3E849121783928AE4D0C6295720458AFA87155ED266900DDCE88C235749A08289EBEAD6754A103

Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet (By similarity). Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1 (By similarity).

Source:http://purl.uniprot.org/SHA-384/955F229A49FE84B10F3E849121783928AE4D0C6295720458AFA87155ED266900DDCE88C235749A08289EBEAD6754A103

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Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet (By similarity). Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1 (By similarity).