924ADACAF6D964CCBDE0C5DBFF5FD72DFBD6D3CD67BCFCAB6EC8090D5460C653181AA44CDC84A663B0264BE8B0AB0694

The DAD domain regulates activation via by an autoinhibitory interaction with the GBD/FH3 domain. This autoinhibition is released upon competitive binding of an activated GTPase. The release of DAD allows the FH2 domain to then nucleate and elongate nonbranched actin filaments (By similarity).

Source:http://purl.uniprot.org/SHA-384/924ADACAF6D964CCBDE0C5DBFF5FD72DFBD6D3CD67BCFCAB6EC8090D5460C653181AA44CDC84A663B0264BE8B0AB0694

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rdf:type	uniprot:Domain_Annotation
rdfs:comment	The DAD domain regulates activation via by an autoinhibitory interaction with the GBD/FH3 domain. This autoinhibition is released upon competitive binding of an activated GTPase. The release of DAD allows the FH2 domain to then nucleate and elongate nonbranched actin filaments (By similarity).