8E0A4A2B11D69EA19AD17BF86869EC91A2458C94FB1038395D7FCFCCCBB0D40F8CB2C5C9E56B595BA88AB3E9F20DEFB3

Cytoplasmic when it is unstabilized (high level of phosphorylation) or bound to CDH1. Translocates to the nucleus when it is stabilized (low level of phosphorylation). Interaction with GLIS2 and MUC1 promotes nuclear translocation. Interaction with EMD inhibits nuclear localization. The majority of beta-catenin is localized to the cell membrane. In interphase, colocalizes with CROCC between CEP250 puncta at the proximal end of centrioles, and this localization is dependent on CROCC and CEP250. In mitosis, when NEK2 activity increases, it localizes to centrosomes at spindle poles independent of CROCC. Co-localizes with CDK5 in the cell-cell contacts and plasma membrane of undifferentiated and differentiated neuroblastoma cells (By similarity).

Source:http://purl.uniprot.org/SHA-384/8E0A4A2B11D69EA19AD17BF86869EC91A2458C94FB1038395D7FCFCCCBB0D40F8CB2C5C9E56B595BA88AB3E9F20DEFB3

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Statements in which the resource exists as a subject.
Predicate	Object
rdf:type	uniprot:Subcellular_Location_Annotation
rdfs:comment	Cytoplasmic when it is unstabilized (high level of phosphorylation) or bound to CDH1. Translocates to the nucleus when it is stabilized (low level of phosphorylation). Interaction with GLIS2 and MUC1 promotes nuclear translocation. Interaction with EMD inhibits nuclear localization. The majority of beta-catenin is localized to the cell membrane. In interphase, colocalizes with CROCC between CEP250 puncta at the proximal end of centrioles, and this localization is dependent on CROCC and CEP250. In mitosis, when NEK2 activity increases, it localizes to centrosomes at spindle poles independent of CROCC. Co-localizes with CDK5 in the cell-cell contacts and plasma membrane of undifferentiated and differentiated neuroblastoma cells (By similarity).
uniprot:locatedIn	http://purl.uniprot.org/SHA-384/82DF273C49D4740824D076CE0B588A3D85A9B9EC9220E344E55FCBE..., http://purl.uniprot.org/SHA-384/6FF552B449821511A8030FB8A5C0B8BE7B12009C85B43BC216A9D46..., http://purl.uniprot.org/SHA-384/9ECE44625C28DFEA6DCE1F63F358B18832FAFA078EAD2D4D92AD408..., http://purl.uniprot.org/SHA-384/B069ABC4CBF52E7F6BFA4D43092BC0993624F30F205CB09B1BF448F..., http://purl.uniprot.org/SHA-384/59CCF3A8D5EDFB875E3FD3AF8F2315DE7B2B3C812F061271F4FCA49..., http://purl.uniprot.org/SHA-384/0AA8174C15D94E5D12BD86DE96585DC64E1500ECFD4AF77D4A132C2..., http://purl.uniprot.org/SHA-384/1A18714910831A0542A0FAF3809F6D748067AB690B7B6A3CEC2D60C..., http://purl.uniprot.org/SHA-384/9F90E830835E7E4D7987F639E1230FD561E4EB5F2E300551A8B0318...