8CEEF0A6EE33DF14C4C2BB32F4E2DAC6494EC98D181A07C61FFF699F083A82D72772B2E8F7B3544B094F4B7E82FC97A0

Homodimer, and heterodimer with DDX39A. Component of the THO complex, which is composed of THOC1, THOC2, THOC5, THOC6 and THOC7. Together with THOC3, ALYREF/THOC4 and DDX39B, THO forms the transcription/export (TREX) complex. Component of the spliceosome. Interacts directly with U2AF2. Interacts directly with ALYREF/THOC4 and is necessary for ALYREF/THOC4 recruitment to spliced mRNA. Interacts with RBM8A, RNPS1 and SRRM1. Interacts with FYTTD1/UIF and THOC1 (By similarity).

Source:http://purl.uniprot.org/SHA-384/8CEEF0A6EE33DF14C4C2BB32F4E2DAC6494EC98D181A07C61FFF699F083A82D72772B2E8F7B3544B094F4B7E82FC97A0

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Homodimer, and heterodimer with DDX39A. Component of the THO complex, which is composed of THOC1, THOC2, THOC5, THOC6 and THOC7. Together with THOC3, ALYREF/THOC4 and DDX39B, THO forms the transcription/export (TREX) complex. Component of the spliceosome. Interacts directly with U2AF2. Interacts directly with ALYREF/THOC4 and is necessary for ALYREF/THOC4 recruitment to spliced mRNA. Interacts with RBM8A, RNPS1 and SRRM1. Interacts with FYTTD1/UIF and THOC1 (By similarity).