83001459C4874B7E1323A22D8E62AF292345E371515EE70C14A9DB0EEB90FF0341A89FEB38F5364D41BF3086F269C9B4

Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis (By similarity).

Source:http://purl.uniprot.org/SHA-384/83001459C4874B7E1323A22D8E62AF292345E371515EE70C14A9DB0EEB90FF0341A89FEB38F5364D41BF3086F269C9B4

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Predicate	Object
rdf:type	uniprot:Function_Annotation
rdfs:comment	Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis (By similarity).