7BE569BADCEBC2DAB6089E7B0C64BE5F866132C7FBEF79457FA0B5DEF766FEA87CC64B563D973904858EAB2825B37C7C

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Source:http://purl.uniprot.org/SHA-384/7BE569BADCEBC2DAB6089E7B0C64BE5F866132C7FBEF79457FA0B5DEF766FEA87CC64B563D973904858EAB2825B37C7C

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Predicate	Object
rdf:type	uniprot:Function_Annotation
rdfs:comment	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.