69CFEA9E2990FDF367A7185FD24809F983493CB4BCCF5D485B7DC47B452BCE338D289CB78150E41E00B8733C22A7BFB5

Toxic component of a toxin-antitoxin (TA) module. A probable translation-independent mRNA interferase. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation; this blockage is overcome (after 90 minutes) by subsequent expression of antitoxin HicB. Overexpression causes cleavage of a number of mRNAs and tmRNA, in a translation-independent fashion, suggesting this is an mRNA interferase.

Source:http://purl.uniprot.org/SHA-384/69CFEA9E2990FDF367A7185FD24809F983493CB4BCCF5D485B7DC47B452BCE338D289CB78150E41E00B8733C22A7BFB5

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Toxic component of a toxin-antitoxin (TA) module. A probable translation-independent mRNA interferase. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation; this blockage is overcome (after 90 minutes) by subsequent expression of antitoxin HicB. Overexpression causes cleavage of a number of mRNAs and tmRNA, in a translation-independent fashion, suggesting this is an mRNA interferase.