Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-K controls genes such as mpb70 and mpb83. However, in strains with the start codon mutation (AUA), there is a decrease in sigK expression, thus affecting SigK-regulated genes expression as well.
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Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-K controls genes such as mpb70 and mpb83. However, in strains with the start codon mutation (AUA), there is a decrease in sigK expression, thus affecting SigK-regulated genes expression as well.
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