Cells lacking this gene accumulate 7,8-didemethyl-8-hydroxy-5-deazariboflavin (Fo) to five times the wild-type levels but do not produce F420. They are also unable to decolorize triphenylmethane dye, and are sensitive to oxidative stress caused by the redox-cycling agents plumbagin and menadione.
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Cells lacking this gene accumulate 7,8-didemethyl-8-hydroxy-5-deazariboflavin (Fo) to five times the wild-type levels but do not produce F420. They are also unable to decolorize triphenylmethane dye, and are sensitive to oxidative stress caused by the redox-cycling agents plumbagin and menadione.
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