360A43D71CBAA03EDAF5C86CE9C2A1D4ADE87A613597CCCC65614DEA01740F8817B20A6D55F020E88FD94E39AC8BA722

Embryonic lethality and sirenomelia were observed only in BMP null embryos in which one or two copies of TSG were also missing. When TSG and BMP7 are mutated, the siren phenotype results from the fusion of the limb buds in the ventroposterior midline owing to a paucity of posterior ventral mesoderm.

Source:http://purl.uniprot.org/SHA-384/360A43D71CBAA03EDAF5C86CE9C2A1D4ADE87A613597CCCC65614DEA01740F8817B20A6D55F020E88FD94E39AC8BA722

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rdf:type	uniprot:Disruption_Phenotype_Annotation
rdfs:comment	Embryonic lethality and sirenomelia were observed only in BMP null embryos in which one or two copies of TSG were also missing. When TSG and BMP7 are mutated, the siren phenotype results from the fusion of the limb buds in the ventroposterior midline owing to a paucity of posterior ventral mesoderm.