1415245AE40F002CC701EDF9F1B7CB196E1FD0BFD142954B54D869C526C35DB1A297C3E8D39F6F2B0EBE5881C472C6E8

Some of the most genetically diverse regions of the viral genome are present in Env. They are called variable regions 1 through 5 (V1 through V5). Coreceptor usage of gp120 is determined mainly by the primary structure of the third variable region (V3) in the outer domain of gp120. Binding to CCR5 involves a region adjacent in addition to V3 (By similarity).

Source:http://purl.uniprot.org/SHA-384/1415245AE40F002CC701EDF9F1B7CB196E1FD0BFD142954B54D869C526C35DB1A297C3E8D39F6F2B0EBE5881C472C6E8

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Some of the most genetically diverse regions of the viral genome are present in Env. They are called variable regions 1 through 5 (V1 through V5). Coreceptor usage of gp120 is determined mainly by the primary structure of the third variable region (V3) in the outer domain of gp120. Binding to CCR5 involves a region adjacent in addition to V3 (By similarity).