Source:http://linkedlifedata.com/resource/geneontology/id/GO:0080188
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rdf:type | |
skos:definition |
"An epigenetic RNA-based gene silencing process first elucidated in plants whereby 24-nt small interfering RNAs (siRNAs) guide DNA methyltransferases to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. In general this process consists of three phases: biogenesis of siRNAs, scaffold RNA production, and the formation of the guiding complex that recruits de novo DNA methyltransferases to the target loci." [PMID:21420348]
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skos:inScheme | |
skos:prefLabel |
RNA-directed DNA methylation
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skos:altLabel |
RdDM
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skos:broader |