Source:http://linkedlifedata.com/resource/geneontology/id/GO:0051482
Predicate | Object |
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rdf:type | |
skos:definition |
"Any process that increases the concentration of calcium ions in the cytosol that occurs as part of a PLC-activating G-protein coupled receptor signaling pathway. G-protein-activated PLC hydrolyses phosphatidylinositol-bisphosphate (PIP2) to release diacylglycerol (DAG) and inositol trisphosphate (IP3). IP3 then binds to calcium release channels in the endoplasmic reticulum (ER) to trigger calcium ion release into the cytosol." [GOC:ai, GOC:signaling]
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skos:inScheme | |
skos:prefLabel |
elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
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skos:altLabel |
elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger
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skos:broader | |
skos:relatedSynonym |
elevation of calcium ion concentration in cytosol during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating),
elevation of cytosolic calcium ion concentration during G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)
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skos:broadSynonym |
elevation of calcium ion concentration in cytoplasm during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating),
elevation of cytoplasmic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating),
elevation of cytoplasmic calcium ion concentration during G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)
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