Source:http://linkedlifedata.com/resource/geneontology/id/GO:0042800
Predicate | Object |
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rdf:type | |
skos:definition |
"Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 4). This reaction is the addition of a methyl group onto lysine at position 4 of the histone H3 protein." [PMID:12086618]
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skos:inScheme | |
skos:prefLabel |
histone methyltransferase activity (H3-K4 specific)
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skos:altLabel |
histone H3 lysine 4-specific methyltransferase activity,
histone lysine N-methyltransferase activity (H3-K4 specific),
histone methylase activity (H3-K4 specific)
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skos:notation |
Reactome:REACT_27174 "Prdm9 Trimethylates Histone H3 (murine, bovine), Bos taurus",
Reactome:REACT_27242 "Trimethylation of Histone H3 by PRDM9, Homo sapiens",
Reactome:REACT_27263 "Prdm9 Trimethylates Histone H3 at Lysine-4, Mus musculus"
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skos:note |
Note that in some species, the methyl group may be added to a lysine in a slightly different position of the histone H3 protein, but that this term still applies.
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skos:broader |