Source:http://linkedlifedata.com/resource/geneontology/id/GO:0035105
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"The transfer of a sterol regulatory element binding protein (SREBP) into the nucleus, across the nuclear membrane, in response to altered levels of one or more lipids. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes." [GOC:bf, GOC:vw, PMID:12923525]
|
| skos:inScheme | |
| skos:prefLabel |
sterol regulatory element binding protein import into nucleus
|
| skos:altLabel |
SREBP import into nucleus,
SREBP import into nucleus involved in sterol depletion response,
sterol depletion response, SREBP import into nucleus,
sterol depletion response, sterol regulatory element binding protein import into nucleus
|
| skos:note |
Note that 'translocation' is sometimes used in the literature to refer to the entire process of protein import into the nucleus, but in GO refers specifically to the step in which a cargo-carrier protein complex moves through the nuclear pore complex.
|
| skos:broader | |
| skos:narrowSynonym |
SREBP nuclear translocation,
sterol depletion response, SREBP nuclear translocation,
sterol depletion response, sterol regulatory element binding protein nuclear translocation,
sterol regulatory element binding protein import into nucleus involved in sterol depletion response,
sterol regulatory element binding protein nuclear translocation,
sterol regulatory element binding protein nuclear translocation involved in sterol depletion response
|