Source:http://linkedlifedata.com/resource/geneontology/id/GO:0033781
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"Catalysis of the reaction: cholesterol + H(+) + NADPH + O(2) = (24S)-24-hydroxycholesterol + H(2)O + NADP(+)." [EC:1.14.13.98, RHEA:22719]
|
| skos:inScheme | |
| skos:prefLabel |
cholesterol 24-hydroxylase activity
|
| skos:altLabel |
cholesterol 24-monooxygenase activity,
cholesterol 24S-hydroxylase activity,
cholesterol,NADPH:oxygen oxidoreductase (24-hydroxylating) activity
|
| skos:notation |
EC:1.14.13.98,
KEGG:R07207,
MetaCyc:1.14.13.98-RXN,
RHEA:22719,
Reactome:REACT_100868 "Cholesterol is hydroxylated to 24-hydroxycholesterol by CYP46A1, Xenopus tropicalis",
Reactome:REACT_10129 "Cholesterol is hydroxylated to 24-hydroxycholesterol by CYP46A1, Homo sapiens",
Reactome:REACT_102867 "Cholesterol is hydroxylated to 24-hydroxycholesterol by CYP46A1, Sus scrofa",
Reactome:REACT_78490 "Cholesterol is hydroxylated to 24-hydroxycholesterol by CYP46A1, Mus musculus",
Reactome:REACT_79067 "Cholesterol is hydroxylated to 24-hydroxycholesterol by CYP46A1, Taeniopygia guttata",
Reactome:REACT_79090 "Cholesterol is hydroxylated to 24-hydroxycholesterol by CYP46A1, Gallus gallus",
Reactome:REACT_79585 "Cholesterol is hydroxylated to 24-hydroxycholesterol by CYP46A1, Canis familiaris",
Reactome:REACT_83550 "Cholesterol is hydroxylated to 24-hydroxycholesterol by CYP46A1, Rattus norvegicus",
Reactome:REACT_94780 "Cholesterol is hydroxylated to 24-hydroxycholesterol by CYP46A1, Bos taurus"
|
| skos:broader | |
| skos:relatedSynonym |
CYP46A1,
cytochrome P450 46A1,
CYP46
|