Source:http://linkedlifedata.com/resource/geneontology/id/GO:0019005
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1)." [PMID:15571813, PMID:15688063]
|
| skos:inScheme | |
| skos:prefLabel |
SCF ubiquitin ligase complex
|
| skos:altLabel |
CDL1 complex,
CRL1 complex,
Cul1-RING ubiquitin ligase complex,
SCF complex,
Skp1/Cul1/F-box protein complex,
cullin-RING ligase 1
|
| skos:notation |
Wikipedia:SCF_complex
|
| skos:broader | |
| skos:narrowSynonym |
SCF complex substrate recognition subunit
|