Source:http://linkedlifedata.com/resource/geneontology/id/GO:0016513
Predicate | Object |
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rdf:type | |
skos:definition |
"A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5'-YGYGGTY-3' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit." [PMID:15156179, PMID:8497254]
|
skos:inScheme | |
skos:prefLabel |
core-binding factor complex
|
skos:altLabel |
CBF complex
|
skos:broader | |
skos:narrowSynonym |
AML1 complex,
PEPB2 complex
|