Source:http://linkedlifedata.com/resource/geneontology/id/GO:0008897
Predicate | Object |
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rdf:type | |
skos:definition |
"Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form." [EC:2.7.8.7, PMID:10320345, PMID:11867633, PMID:8939709]
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skos:inScheme | |
skos:prefLabel |
holo-[acyl-carrier-protein] synthase activity
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skos:altLabel |
4'-phosphopantetheinyl transferase activity,
4'-phosphopantetheinyltransferase activity,
CoA-[4'-phosphopantetheine]:apo-acyl-carrier-protein 4'-pantetheinephosphotransferase activity,
CoA:apo-acyl-carrier-protein pantetheinephosphotransferase activity,
P-pant transferase activity,
PPTase activity,
acyl carrier protein holoprotein (holo-ACP) synthetase activity,
alpha-aminoadipate reductase phosphopantetheinyl transferase activity,
alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity,
alphaaminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity,
coenzyme A:fatty acid synthetase apoenzyme 4'-phosphopantetheine transferase activity,
holo-acyl-carrier-protein synthase activity,
phosphopantetheinyltransferase activity
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skos:notation |
EC:2.7.8.7,
MetaCyc:HOLO-ACP-SYNTH-RXN,
Reactome:REACT_101260 "Phosphopantetheine conjugation of the ACP domain of FAS, Caenorhabditis elegans",
Reactome:REACT_106943 "Phosphopantetheine conjugation of the ACP domain of FAS, Bos taurus",
Reactome:REACT_108901 "Phosphopantetheine conjugation of the ACP domain of FAS, Gallus gallus",
Reactome:REACT_11175 "Phosphopantetheine conjugation of the ACP domain of FAS, Homo sapiens",
Reactome:REACT_114029 "Phosphopantetheine conjugation of the ACP domain of FAS, Dictyostelium discoideum",
Reactome:REACT_114181 "Phosphopantetheine conjugation of the ACP domain of FAS, Xenopus tropicalis",
Reactome:REACT_34019 "Phosphopantetheine conjugation of the ACP domain of FAS, Taeniopygia guttata",
Reactome:REACT_83956 "Phosphopantetheine conjugation of the ACP domain of FAS, Mus musculus",
Reactome:REACT_91705 "Phosphopantetheine conjugation of the ACP domain of FAS, Drosophila melanogaster",
Reactome:REACT_96325 "Phosphopantetheine conjugation of the ACP domain of FAS, Danio rerio",
Reactome:REACT_99586 "Phosphopantetheine conjugation of the ACP domain of FAS, Canis familiaris"
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skos:broader | |
skos:relatedSynonym |
ACPS activity,
AcpS,
acyl carrier protein synthase activity,
acyl carrier protein synthetase activity,
holo-ACP synthase activity,
holo-ACP synthetase activity,
holosynthase activity
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skos:narrowSynonym |
holo-[acyl-carrier-protein] synthase activity,
holo-[peptidyl-carrier protein] synthase activity,
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase activity
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