phosphopantetheinyltransferase activity

Source:http://linkedlifedata.com/resource/geneontology/id/GO:0008897

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
skos:definition
"Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form." [EC:2.7.8.7, PMID:10320345, PMID:11867633, PMID:8939709]
skos:inScheme
skos:prefLabel
holo-[acyl-carrier-protein] synthase activity
skos:altLabel
4'-phosphopantetheinyl transferase activity, 4'-phosphopantetheinyltransferase activity, CoA-[4'-phosphopantetheine]:apo-acyl-carrier-protein 4'-pantetheinephosphotransferase activity, CoA:apo-acyl-carrier-protein pantetheinephosphotransferase activity, P-pant transferase activity, PPTase activity, acyl carrier protein holoprotein (holo-ACP) synthetase activity, alpha-aminoadipate reductase phosphopantetheinyl transferase activity, alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity, alphaaminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity, coenzyme A:fatty acid synthetase apoenzyme 4'-phosphopantetheine transferase activity, holo-acyl-carrier-protein synthase activity, phosphopantetheinyltransferase activity
skos:notation
EC:2.7.8.7, MetaCyc:HOLO-ACP-SYNTH-RXN, Reactome:REACT_101260 "Phosphopantetheine conjugation of the ACP domain of FAS, Caenorhabditis elegans", Reactome:REACT_106943 "Phosphopantetheine conjugation of the ACP domain of FAS, Bos taurus", Reactome:REACT_108901 "Phosphopantetheine conjugation of the ACP domain of FAS, Gallus gallus", Reactome:REACT_11175 "Phosphopantetheine conjugation of the ACP domain of FAS, Homo sapiens", Reactome:REACT_114029 "Phosphopantetheine conjugation of the ACP domain of FAS, Dictyostelium discoideum", Reactome:REACT_114181 "Phosphopantetheine conjugation of the ACP domain of FAS, Xenopus tropicalis", Reactome:REACT_34019 "Phosphopantetheine conjugation of the ACP domain of FAS, Taeniopygia guttata", Reactome:REACT_83956 "Phosphopantetheine conjugation of the ACP domain of FAS, Mus musculus", Reactome:REACT_91705 "Phosphopantetheine conjugation of the ACP domain of FAS, Drosophila melanogaster", Reactome:REACT_96325 "Phosphopantetheine conjugation of the ACP domain of FAS, Danio rerio", Reactome:REACT_99586 "Phosphopantetheine conjugation of the ACP domain of FAS, Canis familiaris"
skos:broader
skos:relatedSynonym
ACPS activity, AcpS, acyl carrier protein synthase activity, acyl carrier protein synthetase activity, holo-ACP synthase activity, holo-ACP synthetase activity, holosynthase activity
skos:narrowSynonym
holo-[acyl-carrier-protein] synthase activity, holo-[peptidyl-carrier protein] synthase activity, L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase activity