GENERIC activation of pro-apoptotic gene products

Statements in which the resource exists as a subject.
Predicate	Object
rdf:type	skos:Concept
skos:definition	"OBSOLETE. The conversion of proteins that induce or sustain apoptosis to an active form." [GOC:mah, GOC:mtg_apoptosis]
skos:inScheme	lld:geneontology
skos:prefLabel	activation of pro-apoptotic gene products
skos:notation	Reactome:REACT_104895 "Caspase-8 activates BID by cleavage, Mus musculus", Reactome:REACT_1320 "Caspase-8 activates BID by cleavage, Homo sapiens", Reactome:REACT_29115 "Caspase-8 activates BID by cleavage, Canis familiaris", Reactome:REACT_78179 "Caspase-8 activates BID by cleavage, Rattus norvegicus", Reactome:REACT_84905 "Caspase-8 activates BID by cleavage, Taeniopygia guttata", Reactome:REACT_88929 "Caspase-8 activates BID by cleavage, Sus scrofa", Reactome:REACT_94301 "Caspase-8 activates BID by cleavage, Gallus gallus", Reactome:REACT_94673 "Caspase-8 activates BID by cleavage, Bos taurus", Reactome:REACT_100125 "Granzyme-B activates BID by cleavage, Mus musculus", Reactome:REACT_101486 "Granzyme-B activates BID by cleavage, Canis familiaris", Reactome:REACT_107597 "Granzyme-B activates BID by cleavage, Sus scrofa", Reactome:REACT_112277 "Granzyme-B activates BID by cleavage, Xenopus tropicalis", Reactome:REACT_1610 "Granzyme-B activates BID by cleavage, Homo sapiens", Reactome:REACT_86117 "Granzyme-B activates BID by cleavage, Rattus norvegicus", Reactome:REACT_99921 "Granzyme-B activates BID by cleavage, Bos taurus", Reactome:REACT_100369 "Activation of BAD and translocation to mitochondria, Danio rerio", Reactome:REACT_101132 "Activation of BMF and translocation to mitochondria, Taeniopygia guttata", Reactome:REACT_101251 "Activation, translocation and oligomerization of BAX, Danio rerio", Reactome:REACT_101322 "Activation of BIM and translocation to mitochondria, Canis familiaris", Reactome:REACT_101888 "Activation of BAD and translocation to mitochondria, Sus scrofa", Reactome:REACT_102426 "Activation and oligomerization of BAK protein, Mus musculus", Reactome:REACT_102689 "Activation of BH3-only proteins, Canis familiaris", Reactome:REACT_103613 "Activation of BIM and translocation to mitochondria, Bos taurus", Reactome:REACT_103971 "Caspase-8 is formed from procaspase-8, Sus scrofa", Reactome:REACT_105161 "Activation, translocation and oligomerization of BAX, Canis familiaris", Reactome:REACT_105349 "tBID activates BAK protein, Mus musculus", Reactome:REACT_105646 "Activation and oligomerization of BAK protein, Taeniopygia guttata", Reactome:REACT_106071 "Activation, myristolyation of BID and translocation to mitochondria, Sus scrofa", Reactome:REACT_106739 "tBID activates BAK protein, Bos taurus", Reactome:REACT_107241 "tBID activates BAK protein, Sus scrofa", Reactome:REACT_108564 "Activation, myristolyation of BID and translocation to mitochondria, Taeniopygia guttata", Reactome:REACT_108722 "Activation, myristolyation of BID and translocation to mitochondria, Xenopus tropicalis", Reactome:REACT_108875 "tBID activates BAK protein, Canis familiaris", Reactome:REACT_110022 "Activation of BAD and translocation to mitochondria, Rattus norvegicus", Reactome:REACT_110545 "Activation, translocation and oligomerization of BAX, Rattus norvegicus", Reactome:REACT_110702 "Activation of BAD and translocation to mitochondria, Mus musculus", Reactome:REACT_110737 "Activation and oligomerization of BAK protein, Rattus norvegicus", Reactome:REACT_112012 "Activation of BIM and translocation to mitochondria, Xenopus tropicalis", Reactome:REACT_112394 "Activation of NOXA and translocation to mitochondria, Canis familiaris", Reactome:REACT_112824 "Caspase-8 is formed from procaspase-8, Caenorhabditis elegans", Reactome:REACT_112867 "Activation of NOXA and translocation to mitochondria, Sus scrofa", Reactome:REACT_113401 "Activation of NOXA and translocation to mitochondria, Rattus norvegicus", Reactome:REACT_115069 "Activation of BAD and translocation to mitochondria, Xenopus tropicalis", Reactome:REACT_115317 "Activation of NOXA and translocation to mitochondria, Mus musculus", Reactome:REACT_1194 "Activation of NOXA and translocation to mitochondria, Homo sapiens", Reactome:REACT_121 "Activation of PUMA and translocation to mitochondria, Homo sapiens", Reactome:REACT_1424 "tBID activates BAK protein, Homo sapiens", Reactome:REACT_1503 "Caspase-8 is formed from procaspase-8, Homo sapiens", Reactome:REACT_1650 "Activation of BIM and translocation to mitochondria, Homo sapiens", Reactome:REACT_2100 "Activation of BMF and translocation to mitochondria, Homo sapiens", Reactome:REACT_28422 "Activation and oligomerization of BAK protein, Bos taurus", Reactome:REACT_30650 "Activation of BMF and translocation to mitochondria, Xenopus tropicalis", Reactome:REACT_31592 "Activation of BIM and translocation to mitochondria, Sus scrofa", Reactome:REACT_32445 "Activation of BH3-only proteins, Sus scrofa", Reactome:REACT_33117 "Activation of BH3-only proteins, Gallus gallus", Reactome:REACT_33493 "Activation of BH3-only proteins, Danio rerio", Reactome:REACT_34491 "Caspase-8 is formed from procaspase-8, Canis familiaris", Reactome:REACT_549 "Activation of BAD and translocation to mitochondria, Homo sapiens", Reactome:REACT_584 "Activation, translocation and oligomerization of BAX, Homo sapiens", Reactome:REACT_697 "Activation of BH3-only proteins, Homo sapiens", Reactome:REACT_701 "Activation, myristolyation of BID and translocation to mitochondria, Homo sapiens", Reactome:REACT_707 "Activation and oligomerization of BAK protein, Homo sapiens", Reactome:REACT_77164 "Caspase-8 is formed from procaspase-8, Taeniopygia guttata", Reactome:REACT_77838 "Activation of BMF and translocation to mitochondria, Gallus gallus", Reactome:REACT_79385 "Activation of BMF and translocation to mitochondria, Rattus norvegicus", Reactome:REACT_79715 "Activation, myristolyation of BID and translocation to mitochondria, Mus musculus", Reactome:REACT_79801 "Activation of BH3-only proteins, Taeniopygia guttata", Reactome:REACT_80000 "tBID activates BAK protein, Taeniopygia guttata", Reactome:REACT_81120 "Activation and oligomerization of BAK protein, Gallus gallus", Reactome:REACT_81817 "Caspase-8 is formed from procaspase-8, Gallus gallus", Reactome:REACT_82840 "Activation, translocation and oligomerization of BAX, Sus scrofa", Reactome:REACT_85149 "Caspase-8 is formed from procaspase-8, Bos taurus", Reactome:REACT_85403 "Activation and oligomerization of BAK protein, Canis familiaris", Reactome:REACT_85478 "Activation, myristolyation of BID and translocation to mitochondria, Canis familiaris", Reactome:REACT_85639 "Activation, translocation and oligomerization of BAX, Xenopus tropicalis", Reactome:REACT_85678 "Activation of BMF and translocation to mitochondria, Mus musculus", Reactome:REACT_85851 "Activation and oligomerization of BAK protein, Sus scrofa", Reactome:REACT_86237 "Caspase-8 is formed from procaspase-8, Mus musculus", Reactome:REACT_87139 "Caspase-8 is formed from procaspase-8, Rattus norvegicus", Reactome:REACT_87505 "Activation, translocation and oligomerization of BAX, Bos taurus", Reactome:REACT_89382 "Activation of BIM and translocation to mitochondria, Mus musculus", Reactome:REACT_89481 "Activation of BMF and translocation to mitochondria, Canis familiaris", Reactome:REACT_90515 "Activation, translocation and oligomerization of BAX, Mus musculus", Reactome:REACT_91640 "Activation of BH3-only proteins, Rattus norvegicus", Reactome:REACT_91879 "Activation of BH3-only proteins, Mus musculus", Reactome:REACT_92391 "Caspase-8 is formed from procaspase-8, Danio rerio", Reactome:REACT_92522 "Activation of BMF and translocation to mitochondria, Bos taurus", Reactome:REACT_93668 "Activation of BIM and translocation to mitochondria, Rattus norvegicus", Reactome:REACT_93967 "tBID activates BAK protein, Rattus norvegicus", Reactome:REACT_95412 "Activation, myristolyation of BID and translocation to mitochondria, Bos taurus", Reactome:REACT_95730 "Activation of BAD and translocation to mitochondria, Bos taurus", Reactome:REACT_97025 "Activation of BH3-only proteins, Xenopus tropicalis", Reactome:REACT_97320 "Activation, myristolyation of BID and translocation to mitochondria, Gallus gallus", Reactome:REACT_97426 "Activation of BH3-only proteins, Bos taurus", Reactome:REACT_98282 "Activation, translocation and oligomerization of BAX, Taeniopygia guttata", Reactome:REACT_98335 "Activation, myristolyation of BID and translocation to mitochondria, Rattus norvegicus"

rdf:type

skos:Concept

skos:inScheme

lld:geneontology

skos:notation

Reactome:REACT_104895 "Caspase-8 activates BID by cleavage, Mus musculus", Reactome:REACT_1320 "Caspase-8 activates BID by cleavage, Homo sapiens", Reactome:REACT_29115 "Caspase-8 activates BID by cleavage, Canis familiaris", Reactome:REACT_78179 "Caspase-8 activates BID by cleavage, Rattus norvegicus", Reactome:REACT_84905 "Caspase-8 activates BID by cleavage, Taeniopygia guttata", Reactome:REACT_88929 "Caspase-8 activates BID by cleavage, Sus scrofa", Reactome:REACT_94301 "Caspase-8 activates BID by cleavage, Gallus gallus", Reactome:REACT_94673 "Caspase-8 activates BID by cleavage, Bos taurus", Reactome:REACT_100125 "Granzyme-B activates BID by cleavage, Mus musculus", Reactome:REACT_101486 "Granzyme-B activates BID by cleavage, Canis familiaris", Reactome:REACT_107597 "Granzyme-B activates BID by cleavage, Sus scrofa", Reactome:REACT_112277 "Granzyme-B activates BID by cleavage, Xenopus tropicalis", Reactome:REACT_1610 "Granzyme-B activates BID by cleavage, Homo sapiens", Reactome:REACT_86117 "Granzyme-B activates BID by cleavage, Rattus norvegicus", Reactome:REACT_99921 "Granzyme-B activates BID by cleavage, Bos taurus", Reactome:REACT_100369 "Activation of BAD and translocation to mitochondria, Danio rerio", Reactome:REACT_101132 "Activation of BMF and translocation to mitochondria, Taeniopygia guttata", Reactome:REACT_101251 "Activation, translocation and oligomerization of BAX, Danio rerio", Reactome:REACT_101322 "Activation of BIM and translocation to mitochondria, Canis familiaris", Reactome:REACT_101888 "Activation of BAD and translocation to mitochondria, Sus scrofa", Reactome:REACT_102426 "Activation and oligomerization of BAK protein, Mus musculus", Reactome:REACT_102689 "Activation of BH3-only proteins, Canis familiaris", Reactome:REACT_103613 "Activation of BIM and translocation to mitochondria, Bos taurus", Reactome:REACT_103971 "Caspase-8 is formed from procaspase-8, Sus scrofa", Reactome:REACT_105161 "Activation, translocation and oligomerization of BAX, Canis familiaris", Reactome:REACT_105349 "tBID activates BAK protein, Mus musculus", Reactome:REACT_105646 "Activation and oligomerization of BAK protein, Taeniopygia guttata", Reactome:REACT_106071 "Activation, myristolyation of BID and translocation to mitochondria, Sus scrofa", Reactome:REACT_106739 "tBID activates BAK protein, Bos taurus", Reactome:REACT_107241 "tBID activates BAK protein, Sus scrofa", Reactome:REACT_108564 "Activation, myristolyation of BID and translocation to mitochondria, Taeniopygia guttata", Reactome:REACT_108722 "Activation, myristolyation of BID and translocation to mitochondria, Xenopus tropicalis", Reactome:REACT_108875 "tBID activates BAK protein, Canis familiaris", Reactome:REACT_110022 "Activation of BAD and translocation to mitochondria, Rattus norvegicus", Reactome:REACT_110545 "Activation, translocation and oligomerization of BAX, Rattus norvegicus", Reactome:REACT_110702 "Activation of BAD and translocation to mitochondria, Mus musculus", Reactome:REACT_110737 "Activation and oligomerization of BAK protein, Rattus norvegicus", Reactome:REACT_112012 "Activation of BIM and translocation to mitochondria, Xenopus tropicalis", Reactome:REACT_112394 "Activation of NOXA and translocation to mitochondria, Canis familiaris", Reactome:REACT_112824 "Caspase-8 is formed from procaspase-8, Caenorhabditis elegans", Reactome:REACT_112867 "Activation of NOXA and translocation to mitochondria, Sus scrofa", Reactome:REACT_113401 "Activation of NOXA and translocation to mitochondria, Rattus norvegicus", Reactome:REACT_115069 "Activation of BAD and translocation to mitochondria, Xenopus tropicalis", Reactome:REACT_115317 "Activation of NOXA and translocation to mitochondria, Mus musculus", Reactome:REACT_1194 "Activation of NOXA and translocation to mitochondria, Homo sapiens", Reactome:REACT_121 "Activation of PUMA and translocation to mitochondria, Homo sapiens", Reactome:REACT_1424 "tBID activates BAK protein, Homo sapiens", Reactome:REACT_1503 "Caspase-8 is formed from procaspase-8, Homo sapiens", Reactome:REACT_1650 "Activation of BIM and translocation to mitochondria, Homo sapiens", Reactome:REACT_2100 "Activation of BMF and translocation to mitochondria, Homo sapiens", Reactome:REACT_28422 "Activation and oligomerization of BAK protein, Bos taurus", Reactome:REACT_30650 "Activation of BMF and translocation to mitochondria, Xenopus tropicalis", Reactome:REACT_31592 "Activation of BIM and translocation to mitochondria, Sus scrofa", Reactome:REACT_32445 "Activation of BH3-only proteins, Sus scrofa", Reactome:REACT_33117 "Activation of BH3-only proteins, Gallus gallus", Reactome:REACT_33493 "Activation of BH3-only proteins, Danio rerio", Reactome:REACT_34491 "Caspase-8 is formed from procaspase-8, Canis familiaris", Reactome:REACT_549 "Activation of BAD and translocation to mitochondria, Homo sapiens", Reactome:REACT_584 "Activation, translocation and oligomerization of BAX, Homo sapiens", Reactome:REACT_697 "Activation of BH3-only proteins, Homo sapiens", Reactome:REACT_701 "Activation, myristolyation of BID and translocation to mitochondria, Homo sapiens", Reactome:REACT_707 "Activation and oligomerization of BAK protein, Homo sapiens", Reactome:REACT_77164 "Caspase-8 is formed from procaspase-8, Taeniopygia guttata", Reactome:REACT_77838 "Activation of BMF and translocation to mitochondria, Gallus gallus", Reactome:REACT_79385 "Activation of BMF and translocation to mitochondria, Rattus norvegicus", Reactome:REACT_79715 "Activation, myristolyation of BID and translocation to mitochondria, Mus musculus", Reactome:REACT_79801 "Activation of BH3-only proteins, Taeniopygia guttata", Reactome:REACT_80000 "tBID activates BAK protein, Taeniopygia guttata", Reactome:REACT_81120 "Activation and oligomerization of BAK protein, Gallus gallus", Reactome:REACT_81817 "Caspase-8 is formed from procaspase-8, Gallus gallus", Reactome:REACT_82840 "Activation, translocation and oligomerization of BAX, Sus scrofa", Reactome:REACT_85149 "Caspase-8 is formed from procaspase-8, Bos taurus", Reactome:REACT_85403 "Activation and oligomerization of BAK protein, Canis familiaris", Reactome:REACT_85478 "Activation, myristolyation of BID and translocation to mitochondria, Canis familiaris", Reactome:REACT_85639 "Activation, translocation and oligomerization of BAX, Xenopus tropicalis", Reactome:REACT_85678 "Activation of BMF and translocation to mitochondria, Mus musculus", Reactome:REACT_85851 "Activation and oligomerization of BAK protein, Sus scrofa", Reactome:REACT_86237 "Caspase-8 is formed from procaspase-8, Mus musculus", Reactome:REACT_87139 "Caspase-8 is formed from procaspase-8, Rattus norvegicus", Reactome:REACT_87505 "Activation, translocation and oligomerization of BAX, Bos taurus", Reactome:REACT_89382 "Activation of BIM and translocation to mitochondria, Mus musculus", Reactome:REACT_89481 "Activation of BMF and translocation to mitochondria, Canis familiaris", Reactome:REACT_90515 "Activation, translocation and oligomerization of BAX, Mus musculus", Reactome:REACT_91640 "Activation of BH3-only proteins, Rattus norvegicus", Reactome:REACT_91879 "Activation of BH3-only proteins, Mus musculus", Reactome:REACT_92391 "Caspase-8 is formed from procaspase-8, Danio rerio", Reactome:REACT_92522 "Activation of BMF and translocation to mitochondria, Bos taurus", Reactome:REACT_93668 "Activation of BIM and translocation to mitochondria, Rattus norvegicus", Reactome:REACT_93967 "tBID activates BAK protein, Rattus norvegicus", Reactome:REACT_95412 "Activation, myristolyation of BID and translocation to mitochondria, Bos taurus", Reactome:REACT_95730 "Activation of BAD and translocation to mitochondria, Bos taurus", Reactome:REACT_97025 "Activation of BH3-only proteins, Xenopus tropicalis", Reactome:REACT_97320 "Activation, myristolyation of BID and translocation to mitochondria, Gallus gallus", Reactome:REACT_97426 "Activation of BH3-only proteins, Bos taurus", Reactome:REACT_98282 "Activation, translocation and oligomerization of BAX, Taeniopygia guttata", Reactome:REACT_98335 "Activation, myristolyation of BID and translocation to mitochondria, Rattus norvegicus"