Predicate | Object |
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rdf:type | |
skos:definition |
"A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome." [PMID:11019806, PMID:12186635, PMID:14570571]
|
skos:inScheme | |
skos:prefLabel |
signalosome
|
skos:altLabel |
CSN
|
skos:broader | |
skos:narrowSynonym |
COP9 complex
|