Source:http://linkedlifedata.com/resource/geneontology/id/GO:0007200
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG)." [GOC:dph, GOC:mah, GOC:signaling, GOC:tb, ISBN:0815316194]
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| skos:inScheme | |
| skos:prefLabel |
phospholipase C-activating G-protein coupled receptor signaling pathway
|
| skos:altLabel |
G protein signaling, coupled to IP3 second messenger (phospholipase C activating),
G protein signalling, coupled to IP3 second messenger (phospholipase C activating),
G-protein coupled receptor signaling pathway coupled to IP3 second messenger,
G-protein signaling, coupled to IP3 second messenger (phospholipase C activating),
G-protein signalling, coupled to IP3 second messenger (phospholipase C activating),
PLC-activating GPCR signaling pathway
|
| skos:note |
This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase C (PLC) activity.
|
| skos:broader | |
| skos:relatedSynonym |
activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
|
| skos:narrowSynonym |
phospholipase C-activating dopamine receptor signaling pathway
|