Source:http://linkedlifedata.com/resource/geneontology/id/GO:0007188
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP (cAMP)." [GOC:mah, GOC:signaling, ISBN:0815316194]
|
| skos:inScheme | |
| skos:prefLabel |
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
|
| skos:altLabel |
G protein signaling, coupled to cAMP nucleotide second messenger,
G protein signaling, coupled to cyclic AMP nucleotide second messenger,
G protein signalling, coupled to cAMP nucleotide second messenger,
G protein signalling, coupled to cyclic AMP nucleotide second messenger,
G-protein signaling, coupled to cAMP nucleotide second messenger,
G-protein signaling, coupled to cyclic AMP nucleotide second messenger,
G-protein signalling, coupled to cAMP nucleotide second messenger,
G-protein signalling, coupled to cyclic AMP nucleotide second messenger,
GPCR signaling pathway via cAMP second messenger,
GPCR signaling pathway via modulation of adenylate cyclase activity,
adenylate cyclase-modulating GPCR signaling pathway
|
| skos:note |
This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of adenylate-cyclase activity. For steps upstream of adenylate cyclase activity, consider instead annotating to 'regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway ; GO:0010578.
|
| skos:broader |