DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

"A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle." [GOC:go_curators]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

Reactome:REACT_107178 "p53-Dependent G1 DNA Damage Response, Bos taurus", Reactome:REACT_108386 "p53-Dependent G1 DNA Damage Response, Danio rerio", Reactome:REACT_110524 "p53-Dependent G1 DNA Damage Response, Canis familiaris", Reactome:REACT_1625 "p53-Dependent G1 DNA Damage Response, Homo sapiens", Reactome:REACT_30327 "p53-Dependent G1 DNA Damage Response, Rattus norvegicus", Reactome:REACT_33731 "p53-Dependent G1 DNA Damage Response, Dictyostelium discoideum", Reactome:REACT_34116 "p53-Dependent G1 DNA Damage Response, Taeniopygia guttata", Reactome:REACT_80077 "p53-Dependent G1 DNA Damage Response, Arabidopsis thaliana", Reactome:REACT_81499 "p53-Dependent G1 DNA Damage Response, Mus musculus", Reactome:REACT_81576 "p53-Dependent G1 DNA Damage Response, Oryza sativa", Reactome:REACT_82172 "p53-Dependent G1 DNA Damage Response, Xenopus tropicalis", Reactome:REACT_87417 "p53-Dependent G1 DNA Damage Response, Gallus gallus", Reactome:REACT_97071 "p53-Dependent G1 DNA Damage Response, Sus scrofa"