Source:http://linkedlifedata.com/resource/geneontology/id/GO:0006919
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process." [GOC:al, GOC:dph, GOC:jl, GOC:mtg_apoptosis, GOC:tb, PMID:14744432, PMID:18328827, Wikipedia:Caspase]
|
| skos:inScheme | |
| skos:prefLabel |
activation of cysteine-type endopeptidase activity involved in apoptotic process
|
| skos:altLabel |
caspase activation
|
| skos:notation |
Reactome:REACT_103096 "Activation of Pro-Caspase 8, Taeniopygia guttata",
Reactome:REACT_108966 "Activation of Pro-Caspase 8, Danio rerio",
Reactome:REACT_109094 "Activation of Pro-Caspase 8, Canis familiaris",
Reactome:REACT_110733 "Activation of Pro-Caspase 8, Mus musculus",
Reactome:REACT_832 "Activation of Pro-Caspase 8, Homo sapiens",
Reactome:REACT_93871 "Activation of Pro-Caspase 8, Gallus gallus",
Reactome:REACT_96857 "Activation of Pro-Caspase 8, Rattus norvegicus",
Reactome:REACT_96984 "Activation of Pro-Caspase 8, Sus scrofa",
Reactome:REACT_99084 "Activation of Pro-Caspase 8, Bos taurus"
|
| skos:note |
This term should be used when the annotation refers to a process that occurs in a context of apoptotic cell death. To annotate gene products involved in activation of cysteine-type endopeptidases in other cellular process (e.g., cell cycle arrest) that do not necessarily develop into an apoptotic process, please use the more general parent term GO:0097202.
|
| skos:broader | |
| skos:narrowSynonym |
activation of caspase activity,
activation of metacaspase activity
|