Source:http://linkedlifedata.com/resource/geneontology/id/GO:0005242
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"Catalysis of the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself." [GOC:cb, GOC:mah, PMID:14977398]
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| skos:inScheme | |
| skos:prefLabel |
inward rectifier potassium channel activity
|
| skos:altLabel |
Kir channel activity
|
| skos:notation |
Reactome:REACT_111144 "Activation of ATP sensitive Potassium channels in muscle cells, Homo sapiens",
Reactome:REACT_75758 "Activation of classical Kir channels, Homo sapiens",
Reactome:REACT_75810 "Activation of Potassium transport channels, Homo sapiens",
Reactome:REACT_75911 "Activation of ATP sensitive Potassium channels in neuroendocrine cells, Homo sapiens"
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| skos:broader |