Source:http://linkedlifedata.com/resource/geneontology/id/GO:0005024
Predicate | Object |
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rdf:type | |
skos:definition |
"Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate." [GOC:mah, GOC:signaling]
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skos:inScheme | |
skos:prefLabel |
transforming growth factor beta-activated receptor activity
|
skos:altLabel |
TGF-beta receptor activity,
TGFbeta receptor activity,
TGFbeta-activated receptor activity,
TGFbetaR,
transforming growth factor beta receptor activity
|
skos:note |
Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand TGFbeta. For binding to other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.
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skos:broader |