Statements in which the resource exists as a subject.
PredicateObject
rdf:type
skos:definition
"Catalysis of the reaction: L-leucine + ATP + tRNA(Leu) = AMP + diphosphate + 2 H(+) + Leu-tRNA(Leu)." [EC:6.1.1.4, RHEA:11691]
skos:inScheme
skos:prefLabel
leucine-tRNA ligase activity
skos:altLabel
L-leucine:tRNALeu ligase (AMP-forming), leucine translase activity, leucine-tRNA synthetase activity, leucyl-tRNA synthetase activity, leucyl-transfer RNA synthetase activity, leucyl-transfer ribonucleate synthetase activity, leucyl-transfer ribonucleic acid synthetase activity
skos:notation
EC:6.1.1.4, KEGG:R03657, MetaCyc:LEUCINE--TRNA-LIGASE-RXN, RHEA:11691, Reactome:REACT_100022 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Canis familiaris", Reactome:REACT_106387 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Escherichia coli", Reactome:REACT_107697 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Bos taurus", Reactome:REACT_108072 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Oryza sativa", Reactome:REACT_109199 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Dictyostelium discoideum", Reactome:REACT_110915 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Xenopus tropicalis", Reactome:REACT_113044 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Arabidopsis thaliana", Reactome:REACT_15357 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Homo sapiens", Reactome:REACT_15504 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Homo sapiens", Reactome:REACT_28095 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Rattus norvegicus", Reactome:REACT_29175 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Danio rerio", Reactome:REACT_29944 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Sus scrofa", Reactome:REACT_30114 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Bos taurus", Reactome:REACT_30248 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Gallus gallus", Reactome:REACT_30669 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Plasmodium falciparum", Reactome:REACT_31192 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Xenopus tropicalis", Reactome:REACT_31653 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Schizosaccharomyces pombe", Reactome:REACT_33620 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Mycobacterium tuberculosis", Reactome:REACT_34333 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Rattus norvegicus", Reactome:REACT_77035 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Saccharomyces cerevisiae", Reactome:REACT_77387 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Drosophila melanogaster", Reactome:REACT_77701 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Taeniopygia guttata", Reactome:REACT_77860 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Mus musculus", Reactome:REACT_80692 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Arabidopsis thaliana", Reactome:REACT_81044 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Sus scrofa", Reactome:REACT_87398 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Gallus gallus", Reactome:REACT_87517 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Oryza sativa", Reactome:REACT_87858 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Staphylococcus aureus N315", Reactome:REACT_88675 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Taeniopygia guttata", Reactome:REACT_89901 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Canis familiaris", Reactome:REACT_94501 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Dictyostelium discoideum", Reactome:REACT_94533 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Mus musculus", Reactome:REACT_95445 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Danio rerio", Reactome:REACT_98538 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Caenorhabditis elegans", Reactome:REACT_99756 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Drosophila melanogaster"
skos:broader