Source:http://linkedlifedata.com/resource/geneontology/id/GO:0004799
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate." [EC:2.1.1.45, RHEA:12107]
|
| skos:inScheme | |
| skos:prefLabel |
thymidylate synthase activity
|
| skos:altLabel |
5,10-methylenetetrahydrofolate:dUMP C-methyltransferase activity,
TMP synthetase activity,
dTMP synthase activity,
methylenetetrahydrofolate:dUMP C-methyltransferase activity,
thymidylate synthetase activity
|
| skos:notation |
EC:2.1.1.45,
KEGG:R02101,
MetaCyc:THYMIDYLATESYN-RXN,
RHEA:12107,
Reactome:REACT_105743 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Arabidopsis thaliana",
Reactome:REACT_106949 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Schizosaccharomyces pombe",
Reactome:REACT_108055 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Drosophila melanogaster",
Reactome:REACT_108220 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Mus musculus",
Reactome:REACT_1679 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Homo sapiens",
Reactome:REACT_34727 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Taeniopygia guttata",
Reactome:REACT_78293 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Danio rerio",
Reactome:REACT_80685 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Escherichia coli",
Reactome:REACT_82204 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Caenorhabditis elegans",
Reactome:REACT_83275 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Bos taurus",
Reactome:REACT_86925 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Mycobacterium tuberculosis",
Reactome:REACT_90103 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Xenopus tropicalis",
Reactome:REACT_93781 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Canis familiaris",
Reactome:REACT_94977 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Rattus norvegicus",
Reactome:REACT_95603 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Plasmodium falciparum",
Reactome:REACT_95751 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Oryza sativa",
Reactome:REACT_96474 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Saccharomyces cerevisiae",
Reactome:REACT_96780 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Gallus gallus",
Reactome:REACT_97834 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate, Staphylococcus aureus N315"
|
| skos:broader |