Source:http://linkedlifedata.com/resource/geneontology/id/GO:0004708
Predicate | Object |
---|---|
rdf:type | |
skos:definition |
"Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate." [ISBN:0198547684]
|
skos:inScheme | |
skos:prefLabel |
MAP kinase kinase activity
|
skos:altLabel |
ATP:protein phosphotransferase (MAPKKK-activated) activity,
ERK activator kinase activity,
MAPKK activity,
mitogen-activated protein kinase kinase activity
|
skos:notation |
EC:2.7.11.-,
MetaCyc:2.7.12.2-RXN,
Reactome:REACT_21301 "Activation of p38 alpha/beta MAPK, Homo sapiens",
Reactome:REACT_21350 "Activation of p38 alpha/beta MAPK, Mus musculus",
Reactome:REACT_75807 "Activation of p38 MAPK, Homo sapiens"
|
skos:broader | |
skos:relatedSynonym |
MAP kinase or ERK kinase activity,
MAP2K,
MAPKK,
MAPKK1,
MEK1,
MEK2,
MKK,
MKK2,
MKK4,
MKK6,
MKK7,
STK27
|
skos:narrowSynonym |
MAP kinase kinase 4 activity,
MAP kinase kinase 7 activity
|
skos:broadSynonym |
MEK activity
|