Rab-protein geranylgeranyltransferase activity

Source:http://linkedlifedata.com/resource/geneontology/id/GO:0004663

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
skos:definition
"Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family." [EC:2.5.1.60, GOC:mah, PMID:8621375]
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skos:prefLabel
Rab geranylgeranyltransferase activity
skos:altLabel
GGTase-II activity, GGTaseII activity, Rab-protein geranylgeranyltransferase activity, RabGGTase activity, geranylgeranyl-diphosphate,geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity, protein geranylgeranyltransferase type II activity, type II protein geranyl-geranyltransferase activity
skos:notation
EC:2.5.1.60, MetaCyc:2.5.1.60-RXN, MetaCyc:RXN-3701
skos:broader