Source:http://linkedlifedata.com/resource/geneontology/id/GO:0004639
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate." [EC:6.3.2.6, RHEA:22631]
|
| skos:inScheme | |
| skos:prefLabel |
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
|
| skos:altLabel |
4-((N-succinylamino)carbonyl)-5-aminoimidazole ribonucleotide synthetase activity,
4-(N-succinocarboxamide)-5-aminoimidazole synthetase activity,
4-[(N-succinylamino)carbonyl]-5-aminoimidazole ribonucleotide synthetase activity,
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate:L-aspartate ligase (ADP-forming),
5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase activity,
SAICAR synthase activity,
SAICAR synthetase activity,
SAICARs activity,
phosphoribosylaminoimidazole-succinocarboxamide synthase activity,
phosphoribosylaminoimidazole-succinocarboxamide synthetase activity,
phosphoribosylaminoimidazolesuccinocarboxamide synthetase activity
|
| skos:notation |
EC:6.3.2.6,
KEGG:R04591,
MetaCyc:SAICARSYN-RXN,
RHEA:22631,
Reactome:REACT_101197 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi, Danio rerio",
Reactome:REACT_105438 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi, Caenorhabditis elegans",
Reactome:REACT_106342 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi, Mus musculus",
Reactome:REACT_108 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi, Homo sapiens",
Reactome:REACT_108542 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi, Escherichia coli",
Reactome:REACT_110520 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi, Staphylococcus aureus N315",
Reactome:REACT_115530 "5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) + L-aspartate + ATP => 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) + adenosine 5'-diphosphate + orthophosphate, Gallus gallus",
Reactome:REACT_28153 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi, Drosophila melanogaster",
Reactome:REACT_83405 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi, Bos taurus",
Reactome:REACT_85214 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi, Sus scrofa",
Reactome:REACT_86983 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi, Xenopus tropicalis",
Reactome:REACT_87410 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi, Canis familiaris",
Reactome:REACT_88991 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi, Gallus gallus",
Reactome:REACT_94909 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi, Rattus norvegicus",
Reactome:REACT_96782 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi, Taeniopygia guttata"
|
| skos:broader | |
| skos:relatedSynonym |
PurC
|