Source:http://linkedlifedata.com/resource/geneontology/id/GO:0004489
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+." [EC:1.5.1.20]
|
| skos:inScheme | |
| skos:prefLabel |
methylenetetrahydrofolate reductase (NADPH) activity
|
| skos:altLabel |
5,10-CH(2)-H(4)folate reductase activity,
5,10-CH2-H4folate reductase activity,
5,10-methylenetetrahydrofolate reductase (FADH) activity,
5,10-methylenetetrahydrofolate reductase (FADH2) activity,
5,10-methylenetetrahydrofolate reductase (NADPH) activity,
5,10-methylenetetrahydropteroylglutamate reductase activity,
5-methyltetrahydrofolate:(acceptor) oxidoreductase activity,
5-methyltetrahydrofolate:NAD oxidoreductase activity,
5-methyltetrahydrofolate:NAD(+) oxidoreductase activity,
5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity,
5-methyltetrahydrofolate:NAD+ oxidoreductase activity,
5-methyltetrahydrofolate:NADP(+) oxidoreductase activity,
5-methyltetrahydrofolate:NADP+ oxidoreductase activity,
N5,10-methylenetetrahydrofolate reductase activity,
N5,N10-methylenetetrahydrofolate reductase activity,
methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity,
methylenetetrahydrofolate reductase (NADPH(2)) activity,
methylenetetrahydrofolate reductase (NADPH2)
|
| skos:notation |
EC:1.5.1.20,
MetaCyc:1.5.1.20-RXN,
RHEA:19820,
RHEA:19825,
Reactome:REACT_100929 "5,10-methyleneTHF polyglutamate + NADPH + H+ => 5-methylTHF polyglutamate + NADP+, Sus scrofa",
Reactome:REACT_102712 "5,10-methyleneTHF polyglutamate + NADPH + H+ => 5-methylTHF polyglutamate + NADP+, Gallus gallus",
Reactome:REACT_106752 "5,10-methyleneTHF polyglutamate + NADPH + H+ => 5-methylTHF polyglutamate + NADP+, Taeniopygia guttata",
Reactome:REACT_106770 "5,10-methyleneTHF polyglutamate + NADPH + H+ => 5-methylTHF polyglutamate + NADP+, Dictyostelium discoideum",
Reactome:REACT_109034 "5,10-methyleneTHF polyglutamate + NADPH + H+ => 5-methylTHF polyglutamate + NADP+, Xenopus tropicalis",
Reactome:REACT_110093 "5,10-methyleneTHF polyglutamate + NADPH + H+ => 5-methylTHF polyglutamate + NADP+, Danio rerio",
Reactome:REACT_110152 "5,10-methyleneTHF polyglutamate + NADPH + H+ => 5-methylTHF polyglutamate + NADP+, Mus musculus",
Reactome:REACT_11102 "5,10-methyleneTHF polyglutamate + NADPH + H+ => 5-methylTHF polyglutamate + NADP+, Homo sapiens",
Reactome:REACT_29352 "5,10-methyleneTHF polyglutamate + NADPH + H+ => 5-methylTHF polyglutamate + NADP+, Rattus norvegicus",
Reactome:REACT_30478 "5,10-methyleneTHF polyglutamate + NADPH + H+ => 5-methylTHF polyglutamate + NADP+, Canis familiaris",
Reactome:REACT_33585 "5,10-methyleneTHF polyglutamate + NADPH + H+ => 5-methylTHF polyglutamate + NADP+, Escherichia coli",
Reactome:REACT_78371 "5,10-methyleneTHF polyglutamate + NADPH + H+ => 5-methylTHF polyglutamate + NADP+, Caenorhabditis elegans",
Reactome:REACT_96333 "5,10-methyleneTHF polyglutamate + NADPH + H+ => 5-methylTHF polyglutamate + NADP+, Bos taurus",
Reactome:REACT_97871 "5,10-methyleneTHF polyglutamate + NADPH + H+ => 5-methylTHF polyglutamate + NADP+, Oryza sativa",
Reactome:REACT_98681 "5,10-methyleneTHF polyglutamate + NADPH + H+ => 5-methylTHF polyglutamate + NADP+, Drosophila melanogaster"
|
| skos:note |
Includes EC 1.7.99.5.
|
| skos:broader | |
| skos:relatedSynonym |
1.7.99.5,
5,10-methylenetetrahydrofolate reductase (FADH(2)) activity,
MetF,
methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity,
methylenetetrahydrofolate reductase [NAD(P)H]
|
| skos:broadSynonym |
5,10-methylenetetrahydrofolate reductase activity,
5,10-methylenetetrahydrofolic acid reductase activity,
methylenetetrahydrofolate reductase activity,
methylenetetrahydrofolic acid reductase activity,
MTHFR activity,
N(5),N(10)-methylenetetrahydrofolate reductase activity,
N(5,10)-methylenetetrahydrofolate reductase activity
|