Source:http://linkedlifedata.com/resource/geneontology/id/GO:0004435
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H(+)." [EC:3.1.4.11, RHEA:23915]
|
| skos:inScheme | |
| skos:prefLabel |
phosphatidylinositol phospholipase C activity
|
| skos:altLabel |
1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity,
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity,
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity,
PI-PLC activity,
phosphoinositidase C activity,
phosphoinositide phospholipase C activity
|
| skos:notation |
EC:3.1.4.11,
KEGG:R03435,
MetaCyc:3.1.4.11-RXN,
RHEA:23915,
Reactome:REACT_100549 "PLC-gamma1 hydrolyses PIP2, Danio rerio",
Reactome:REACT_101538 "PIP2 hydrolysis, Taeniopygia guttata",
Reactome:REACT_103918 "PIP2 hydrolysis, Xenopus tropicalis",
Reactome:REACT_104013 "PIP2 hydrolysis, Caenorhabditis elegans",
Reactome:REACT_104384 "PLC-gamma1 hydrolyses PIP2, Sus scrofa",
Reactome:REACT_105056 "PIP2 hydrolysis, Canis familiaris",
Reactome:REACT_105753 "PLC-gamma1 hydrolyses PIP2, Gallus gallus",
Reactome:REACT_106433 "PLC-gamma1 hydrolyses PIP2, Rattus norvegicus",
Reactome:REACT_107694 "PIP2 hydrolysis, Gallus gallus",
Reactome:REACT_108661 "PIP2 hydrolysis, Mus musculus",
Reactome:REACT_109774 "Active PLCG1 hydrolyses PIP2, Danio rerio",
Reactome:REACT_111977 "PIP2 hydrolysis, Drosophila melanogaster",
Reactome:REACT_112016 "Active PLCG1 hydrolyses PIP2, Arabidopsis thaliana",
Reactome:REACT_112120 "PLC-gamma1 hydrolyses PIP2, Saccharomyces cerevisiae",
Reactome:REACT_112432 "PLC-gamma1 hydrolyses PIP2, Oryza sativa",
Reactome:REACT_112586 "PIP2 hydrolysis, Oryza sativa",
Reactome:REACT_113026 "PLC-gamma1 hydrolyses PIP2, Drosophila melanogaster",
Reactome:REACT_113134 "PIP2 hydrolysis, Schizosaccharomyces pombe",
Reactome:REACT_113176 "PLC-gamma1 hydrolyses PIP2, Arabidopsis thaliana",
Reactome:REACT_113179 "Active PLCG1 hydrolyses PIP2, Saccharomyces cerevisiae",
Reactome:REACT_113201 "PLC-gamma1 hydrolyses PIP2, Plasmodium falciparum",
Reactome:REACT_113580 "PLC-gamma1 hydrolyses PIP2, Dictyostelium discoideum",
Reactome:REACT_113618 "Active PLCG1 hydrolyses PIP2, Plasmodium falciparum",
Reactome:REACT_113733 "Active PLCG1 hydrolyses PIP2, Dictyostelium discoideum",
Reactome:REACT_113827 "PIP2 hydrolysis, Dictyostelium discoideum",
Reactome:REACT_113870 "PLC-gamma1 hydrolyses PIP2, Schizosaccharomyces pombe",
Reactome:REACT_113925 "Active PLCG1 hydrolyses PIP2, Drosophila melanogaster",
Reactome:REACT_113959 "PIP2 hydrolysis, Arabidopsis thaliana",
Reactome:REACT_114034 "PIP2 hydrolysis, Schizosaccharomyces pombe",
Reactome:REACT_114083 "Active PLCG1 hydrolyses PIP2, Oryza sativa",
Reactome:REACT_114101 "PLC-gamma1 hydrolyses PIP2, Caenorhabditis elegans",
Reactome:REACT_114237 "Active PLCG1 hydrolyses PIP2, Caenorhabditis elegans",
Reactome:REACT_114264 "Active PLCG1 hydrolyses PIP2, Schizosaccharomyces pombe",
Reactome:REACT_114329 "PIP2 hydrolysis, Dictyostelium discoideum",
Reactome:REACT_114608 "PIP2 hydrolysis, Saccharomyces cerevisiae",
Reactome:REACT_114663 "PIP2 hydrolysis, Plasmodium falciparum",
Reactome:REACT_114783 "PIP2 hydrolysis, Caenorhabditis elegans",
Reactome:REACT_115119 "PIP2 hydrolysis, Saccharomyces cerevisiae",
Reactome:REACT_116048 "Active PLCG1 hydrolyses PIP2, Rattus norvegicus",
Reactome:REACT_12078 "Active PLCG1 hydrolyses PIP2, Homo sapiens",
Reactome:REACT_12585 "PLC-gamma1 hydrolyses PIP2, Homo sapiens",
Reactome:REACT_15353 "PIP2 hydrolysis, Homo sapiens",
Reactome:REACT_22318 "PIP2 hydrolysis, Homo sapiens",
Reactome:REACT_22417 "PIP2 hydrolysis, Rattus norvegicus",
Reactome:REACT_28616 "PLC-gamma1 hydrolyses PIP2, Xenopus tropicalis",
Reactome:REACT_31243 "PLC-gamma1 hydrolyses PIP2, Taeniopygia guttata",
Reactome:REACT_34289 "PIP2 hydrolysis, Sus scrofa",
Reactome:REACT_77907 "PIP2 hydrolysis, Danio rerio",
Reactome:REACT_79438 "PIP2 hydrolysis, Bos taurus",
Reactome:REACT_80615 "Active PLCG1 hydrolyses PIP2, Mus musculus",
Reactome:REACT_80913 "Active PLCG1 hydrolyses PIP2, Gallus gallus",
Reactome:REACT_82046 "PIP2 hydrolysis, Danio rerio",
Reactome:REACT_84690 "Active PLCG1 hydrolyses PIP2, Bos taurus",
Reactome:REACT_86163 "PLC-gamma1 hydrolyses PIP2, Bos taurus",
Reactome:REACT_86182 "PLC-gamma1 hydrolyses PIP2, Mus musculus",
Reactome:REACT_87086 "PIP2 hydrolysis, Taeniopygia guttata",
Reactome:REACT_87142 "PIP2 hydrolysis, Bos taurus",
Reactome:REACT_87357 "PIP2 hydrolysis, Mus musculus",
Reactome:REACT_87628 "PIP2 hydrolysis, Drosophila melanogaster",
Reactome:REACT_87970 "Active PLCG1 hydrolyses PIP2, Sus scrofa",
Reactome:REACT_88756 "PIP2 hydrolysis, Xenopus tropicalis",
Reactome:REACT_88910 "Active PLCG1 hydrolyses PIP2, Taeniopygia guttata",
Reactome:REACT_90807 "PIP2 hydrolysis, Sus scrofa",
Reactome:REACT_93506 "Active PLCG1 hydrolyses PIP2, Xenopus tropicalis",
Reactome:REACT_94845 "PIP2 hydrolysis, Rattus norvegicus",
Reactome:REACT_97327 "Active PLCG1 hydrolyses PIP2, Canis familiaris",
Reactome:REACT_97840 "PIP2 hydrolysis, Canis familiaris",
Reactome:REACT_98877 "PIP2 hydrolysis, Gallus gallus",
Reactome:REACT_99371 "PLC-gamma1 hydrolyses PIP2, Canis familiaris"
|
| skos:broader | |
| skos:relatedSynonym |
phosphatidylinositol-4,5-bisphosphate hydrolysis
|
| skos:broadSynonym |
monophosphatidylinositol phosphodiesterase activity,
triphosphoinositide phosphodiesterase activity
|