Source:http://linkedlifedata.com/resource/geneontology/id/GO:0004420
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH." [EC:1.1.1.34, RHEA:15992]
|
| skos:inScheme | |
| skos:prefLabel |
hydroxymethylglutaryl-CoA reductase (NADPH) activity
|
| skos:notation |
EC:1.1.1.34,
KEGG:R02082,
MetaCyc:1.1.1.34-RXN,
RHEA:15992,
Reactome:REACT_100813 "Reduction of HMG-CoA produces mevalonate, Arabidopsis thaliana",
Reactome:REACT_103521 "Reduction of HMG-CoA produces mevalonate, Caenorhabditis elegans",
Reactome:REACT_103848 "Reduction of HMG-CoA produces mevalonate, Saccharomyces cerevisiae",
Reactome:REACT_105607 "Reduction of HMG-CoA produces mevalonate, Gallus gallus",
Reactome:REACT_106886 "Reduction of HMG-CoA produces mevalonate, Bos taurus",
Reactome:REACT_109306 "Reduction of HMG-CoA produces mevalonate, Dictyostelium discoideum",
Reactome:REACT_111022 "Reduction of HMG-CoA produces mevalonate, Drosophila melanogaster",
Reactome:REACT_29404 "Reduction of HMG-CoA produces mevalonate, Canis familiaris",
Reactome:REACT_30181 "Reduction of HMG-CoA produces mevalonate, Taeniopygia guttata",
Reactome:REACT_80613 "Reduction of HMG-CoA produces mevalonate, Mus musculus",
Reactome:REACT_85139 "Reduction of HMG-CoA produces mevalonate, Xenopus tropicalis",
Reactome:REACT_89068 "Reduction of HMG-CoA produces mevalonate, Schizosaccharomyces pombe",
Reactome:REACT_91015 "Reduction of HMG-CoA produces mevalonate, Oryza sativa",
Reactome:REACT_91582 "Reduction of HMG-CoA produces mevalonate, Danio rerio",
Reactome:REACT_9482 "Reduction of HMG-CoA produces mevalonate, Homo sapiens",
Reactome:REACT_97829 "Reduction of HMG-CoA produces mevalonate, Sus scrofa",
Reactome:REACT_99024 "Reduction of HMG-CoA produces mevalonate, Rattus norvegicus"
|
| skos:broader | |
| skos:broadSynonym |
HMG-CoA reductase activity,
3-hydroxy-3-methylglutaryl-coenzyme A reductase activity
|