hydroxymethylglutaryl-CoA lyase activity

Source:http://linkedlifedata.com/resource/geneontology/id/GO:0004419

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
skos:definition
"Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA." [EC:4.1.3.4, RHEA:24407]
skos:inScheme
skos:prefLabel
hydroxymethylglutaryl-CoA lyase activity
skos:altLabel
(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase (acetyl-CoA-forming), (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase activity, 3-hydroxy-3-methylglutarate-CoA lyase activity, 3-hydroxy-3-methylglutaryl coenzyme A lyase activity, 3-hydroxy-3-methylglutaryl-CoA lyase activity, HMG-CoA lyase activity, hydroxymethylglutaryl coenzyme A lyase activity
skos:notation
EC:4.1.3.4, KEGG:R01360, MetaCyc:HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN, RHEA:24407, Reactome:REACT_100202 "HMG CoA => acetoacetic acid + acetyl CoA, Dictyostelium discoideum", Reactome:REACT_104457 "HMG CoA => acetoacetic acid + acetyl CoA, Drosophila melanogaster", Reactome:REACT_105243 "HMG CoA => acetoacetic acid + acetyl CoA, Canis familiaris", Reactome:REACT_108952 "HMG CoA => acetoacetic acid + acetyl CoA, Gallus gallus", Reactome:REACT_110966 "HMG CoA => acetoacetic acid + acetyl CoA, Arabidopsis thaliana", Reactome:REACT_2103 "HMG CoA => acetoacetic acid + acetyl CoA, Homo sapiens", Reactome:REACT_29720 "HMG CoA => acetoacetic acid + acetyl CoA, Oryza sativa", Reactome:REACT_31175 "HMG CoA => acetoacetic acid + acetyl CoA, Taeniopygia guttata", Reactome:REACT_86954 "HMG CoA => acetoacetic acid + acetyl CoA, Mus musculus", Reactome:REACT_89460 "HMG CoA => acetoacetic acid + acetyl CoA, Xenopus tropicalis", Reactome:REACT_90800 "HMG CoA => acetoacetic acid + acetyl CoA, Rattus norvegicus", Reactome:REACT_91737 "HMG CoA => acetoacetic acid + acetyl CoA, Bos taurus", Reactome:REACT_99837 "HMG CoA => acetoacetic acid + acetyl CoA, Danio rerio", Reactome:REACT_99898 "HMG CoA => acetoacetic acid + acetyl CoA, Caenorhabditis elegans"
skos:broader
skos:relatedSynonym
3-hydroxy-3-methylglutaryl CoA cleaving enzyme, hydroxymethylglutaryl coenzyme A-cleaving enzyme