glycine hydroxymethyltransferase activity

"Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine." [EC:2.1.2.1]

glycine hydroxymethyltransferase activity

EC:2.1.2.1, MetaCyc:GLYOHMETRANS-RXN, RHEA:15484, Reactome:REACT_100551 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Taeniopygia guttata", Reactome:REACT_101143 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Canis familiaris", Reactome:REACT_103730 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Oryza sativa", Reactome:REACT_104026 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Plasmodium falciparum", Reactome:REACT_105838 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Danio rerio", Reactome:REACT_106100 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Gallus gallus", Reactome:REACT_106938 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Taeniopygia guttata", Reactome:REACT_108889 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Taeniopygia guttata", Reactome:REACT_109080 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Oryza sativa", Reactome:REACT_110497 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Saccharomyces cerevisiae", Reactome:REACT_110666 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Arabidopsis thaliana", Reactome:REACT_110712 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Xenopus tropicalis", Reactome:REACT_110780 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Mus musculus", Reactome:REACT_111007 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Plasmodium falciparum", Reactome:REACT_11108 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Homo sapiens", Reactome:REACT_11159 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Homo sapiens", Reactome:REACT_112625 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Mycobacterium tuberculosis", Reactome:REACT_112714 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Staphylococcus aureus N315", Reactome:REACT_113302 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Escherichia coli", Reactome:REACT_113467 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Escherichia coli", Reactome:REACT_114244 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Escherichia coli", Reactome:REACT_114305 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Staphylococcus aureus N315", Reactome:REACT_114385 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Staphylococcus aureus N315", Reactome:REACT_114576 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Mycobacterium tuberculosis", Reactome:REACT_115121 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Mycobacterium tuberculosis", Reactome:REACT_1345 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Homo sapiens", Reactome:REACT_30943 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Drosophila melanogaster", Reactome:REACT_31482 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Gallus gallus", Reactome:REACT_31564 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Rattus norvegicus", Reactome:REACT_31591 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Rattus norvegicus", Reactome:REACT_33927 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Mus musculus", Reactome:REACT_33932 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Plasmodium falciparum", Reactome:REACT_34223 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Saccharomyces cerevisiae", Reactome:REACT_77050 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Canis familiaris", Reactome:REACT_77924 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Danio rerio", Reactome:REACT_78152 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Rattus norvegicus", Reactome:REACT_80167 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Saccharomyces cerevisiae", Reactome:REACT_80412 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Oryza sativa", Reactome:REACT_81468 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Bos taurus", Reactome:REACT_82542 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Canis familiaris", Reactome:REACT_84260 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Arabidopsis thaliana", Reactome:REACT_86594 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Bos taurus", Reactome:REACT_88214 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Drosophila melanogaster", Reactome:REACT_88519 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Mus musculus", Reactome:REACT_89705 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Gallus gallus", Reactome:REACT_90130 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Bos taurus", Reactome:REACT_90410 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Drosophila melanogaster", Reactome:REACT_91337 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Xenopus tropicalis", Reactome:REACT_91776 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Caenorhabditis elegans", Reactome:REACT_92924 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Caenorhabditis elegans", Reactome:REACT_93345 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Schizosaccharomyces pombe", Reactome:REACT_93885 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Xenopus tropicalis", Reactome:REACT_95280 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Danio rerio", Reactome:REACT_95373 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Schizosaccharomyces pombe", Reactome:REACT_95737 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Arabidopsis thaliana", Reactome:REACT_97896 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Schizosaccharomyces pombe", Reactome:REACT_99194 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Caenorhabditis elegans"