glutathione-disulfide reductase activity

Source:http://linkedlifedata.com/resource/geneontology/id/GO:0004362

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
skos:definition
"Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+." [EC:1.8.1.7, ISBN:0198506732]
skos:inScheme
skos:prefLabel
glutathione-disulfide reductase activity
skos:altLabel
GSH reductase activity, GSSG reductase activity, NADPH-GSSG reductase activity, NADPH-glutathione reductase activity, NADPH:oxidized-glutathione oxidoreductase activity, glutathione S-reductase activity, glutathione reductase (NADPH) activity, glutathione reductase activity, glutathione-disulphide reductase activity, glutathione:NADP+ oxidoreductase activity
skos:notation
EC:1.8.1.7, MetaCyc:GLUTATHIONE-REDUCT-NADPH-RXN, RHEA:11743, Reactome:REACT_100755 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Plasmodium falciparum", Reactome:REACT_105351 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Mus musculus", Reactome:REACT_106052 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Escherichia coli", Reactome:REACT_107331 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Bos taurus", Reactome:REACT_108894 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Xenopus tropicalis", Reactome:REACT_2220 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Homo sapiens", Reactome:REACT_31135 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Canis familiaris", Reactome:REACT_33636 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Sus scrofa", Reactome:REACT_34766 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Dictyostelium discoideum", Reactome:REACT_82516 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Rattus norvegicus", Reactome:REACT_87466 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Mycobacterium tuberculosis", Reactome:REACT_91212 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Schizosaccharomyces pombe", Reactome:REACT_91373 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Danio rerio", Reactome:REACT_93897 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Caenorhabditis elegans", Reactome:REACT_95299 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Saccharomyces cerevisiae", Reactome:REACT_95410 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Gallus gallus", Reactome:REACT_98360 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Taeniopygia guttata"
skos:note
Note that this function was formerly EC:1.6.4.2.
skos:broader
skos:relatedSynonym
oxidized glutathione reduction