Source:http://linkedlifedata.com/resource/geneontology/id/GO:0004146
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+." [EC:1.5.1.3]
|
| skos:inScheme | |
| skos:prefLabel |
dihydrofolate reductase activity
|
| skos:altLabel |
5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase activity,
7,8-dihydrofolate reductase activity,
NADPH-dihydrofolate reductase activity,
dihydrofolate reductase:thymidylate synthase activity,
dihydrofolate reduction,
dihydrofolic acid reductase activity,
dihydrofolic reductase activity,
folic acid reductase activity,
folic reductase activity,
pteridine reductase:dihydrofolate reductase activity,
tetrahydrofolate dehydrogenase activity,
thymidylate synthetase-dihydrofolate reductase activity
|
| skos:notation |
EC:1.5.1.3,
MetaCyc:DIHYDROFOLATEREDUCT-RXN,
RHEA:15012,
Reactome:REACT_111041 "Salvage - BH2 is reduced to BH4 by DHFR, Homo sapiens",
Reactome:REACT_115762 "Salvage - BH2 is reduced to BH4 by Dhfr, Mus musculus"
|
| skos:broader | |
| skos:relatedSynonym |
DHFR
|