Source:http://linkedlifedata.com/resource/geneontology/id/GO:0003994
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"Catalysis of the reactions: citrate = cis-aconitate + H2O, and cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate." [EC:4.2.1.3, GOC:pde, GOC:vw]
|
| skos:inScheme | |
| skos:prefLabel |
aconitate hydratase activity
|
| skos:altLabel |
aconitase activity,
cis-aconitase activity,
citrate(isocitrate) hydro-lyase (cis-aconitate-forming),
citrate(isocitrate) hydro-lyase activity
|
| skos:notation |
EC:4.2.1.3,
RHEA:10231,
RHEA:22148,
Reactome:REACT_106698 "citrate <=> isocitrate, Saccharomyces cerevisiae",
Reactome:REACT_115701 "citrate <=> isocitrate, Gallus gallus",
Reactome:REACT_116024 "isocitrate <=> citrate, Gallus gallus",
Reactome:REACT_1898 "citrate <=> isocitrate, Homo sapiens",
Reactome:REACT_21262 "isocitrate <=> citrate, Homo sapiens",
Reactome:REACT_30406 "citrate <=> isocitrate, Caenorhabditis elegans",
Reactome:REACT_32627 "citrate <=> isocitrate, Rattus norvegicus",
Reactome:REACT_46526 "citrate <=> isocitrate, Schizosaccharomyces pombe",
Reactome:REACT_77059 "citrate <=> isocitrate, Bos taurus",
Reactome:REACT_77875 "citrate <=> isocitrate, Canis familiaris",
Reactome:REACT_77983 "citrate <=> isocitrate, Dictyostelium discoideum",
Reactome:REACT_78997 "citrate <=> isocitrate, Taeniopygia guttata",
Reactome:REACT_81376 "citrate <=> isocitrate, Mus musculus",
Reactome:REACT_82548 "citrate <=> isocitrate, Xenopus tropicalis",
Reactome:REACT_83980 "citrate <=> isocitrate, Gallus gallus",
Reactome:REACT_86078 "citrate <=> isocitrate, Danio rerio",
Reactome:REACT_90644 "citrate <=> isocitrate, Drosophila melanogaster",
Reactome:REACT_97737 "citrate <=> isocitrate, Sus scrofa"
|
| skos:note |
This is a process composed of two reactions represented by the terms 'GO:0052632 : citrate hydro-lyase (cis-aconitate-forming) activity' and 'GO:0052633 : isocitrate hydro-lyase (cis-aconitate-forming) activity'.
|
| skos:broader | |
| skos:broadSynonym |
citrate hydro-lyase activity
|