Source:http://linkedlifedata.com/resource/geneontology/id/GO:0003917
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle." [PMID:8811192]
|
| skos:inScheme | |
| skos:prefLabel |
DNA topoisomerase type I activity
|
| skos:altLabel |
type I DNA topoisomerase activity,
type I topoisomerase activity
|
| skos:notation |
EC:5.99.1.2,
MetaCyc:5.99.1.2-RXN
|
| skos:note |
Note that a further distinction, between type IA and type IB topoisomerases, is based on sequence or structural similarity between gene products that possess type I catalytic activity.
|
| skos:broader | |
| skos:relatedSynonym |
nicking-closing enzyme activity,
omega-protein activity,
relaxing enzyme activity,
swivelase activity,
untwisting enzyme activity
|
| skos:narrowSynonym |
DNA topoisomerase I activity
|
| skos:broadSynonym |
topoisomerase,
deoxyribonucleate topoisomerase
|