DNA-(apurinic or apyrimidinic site) lyase activity

Source:http://linkedlifedata.com/resource/geneontology/id/GO:0003906

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
skos:definition
"Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate." [EC:4.2.99.18]
skos:inScheme
skos:prefLabel
DNA-(apurinic or apyrimidinic site) lyase activity
skos:altLabel
AP lyase activity, AP site-DNA 5'-phosphomonoester-lyase activity, DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity, deoxyribonuclease (apurinic or apyrimidinic) activity, endodeoxyribonuclease (apurinic or apyrimidinic) activity
skos:notation
EC:4.2.99.18, MetaCyc:4.2.99.18-RXN, Reactome:REACT_103252 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Xenopus tropicalis", Reactome:REACT_1215 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Homo sapiens", Reactome:REACT_32396 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Rattus norvegicus", Reactome:REACT_55273 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Dictyostelium discoideum", Reactome:REACT_79844 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Mus musculus", Reactome:REACT_83849 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Danio rerio", Reactome:REACT_85754 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Sus scrofa", Reactome:REACT_96683 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Bos taurus", Reactome:REACT_97368 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Canis familiaris", Reactome:REACT_99910 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Taeniopygia guttata"
skos:broader
skos:relatedSynonym
E. coli endonuclease III, X-ray endonuclease III, endonuclease VIII activity
skos:narrowSynonym
AP endonuclease class I activity, E. coli endonuclease III activity, Micrococcus luteus UV endonuclease activity, Phage-T(4) UV endonuclease activity, Phage-T4 UV endonuclease activity, micrococcus luteus UV endonuclease
skos:broadSynonym
phage-T4 UV endonuclease