Source:http://linkedlifedata.com/resource/geneontology/id/GO:0003906
Predicate | Object |
---|---|
rdf:type | |
skos:definition |
"Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate." [EC:4.2.99.18]
|
skos:inScheme | |
skos:prefLabel |
DNA-(apurinic or apyrimidinic site) lyase activity
|
skos:altLabel |
AP lyase activity,
AP site-DNA 5'-phosphomonoester-lyase activity,
DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity,
deoxyribonuclease (apurinic or apyrimidinic) activity,
endodeoxyribonuclease (apurinic or apyrimidinic) activity
|
skos:notation |
EC:4.2.99.18,
MetaCyc:4.2.99.18-RXN,
Reactome:REACT_103252 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Xenopus tropicalis",
Reactome:REACT_1215 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Homo sapiens",
Reactome:REACT_32396 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Rattus norvegicus",
Reactome:REACT_55273 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Dictyostelium discoideum",
Reactome:REACT_79844 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Mus musculus",
Reactome:REACT_83849 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Danio rerio",
Reactome:REACT_85754 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Sus scrofa",
Reactome:REACT_96683 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Bos taurus",
Reactome:REACT_97368 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Canis familiaris",
Reactome:REACT_99910 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Taeniopygia guttata"
|
skos:broader | |
skos:relatedSynonym |
E. coli endonuclease III,
X-ray endonuclease III,
endonuclease VIII activity
|
skos:narrowSynonym |
AP endonuclease class I activity,
E. coli endonuclease III activity,
Micrococcus luteus UV endonuclease activity,
Phage-T(4) UV endonuclease activity,
Phage-T4 UV endonuclease activity,
micrococcus luteus UV endonuclease
|
skos:broadSynonym |
phage-T4 UV endonuclease
|