3-beta-hydroxy-delta5-steroid dehydrogenase activity

"Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H(+)." [EC:1.1.1.145]

3-beta-hydroxy-delta5-steroid dehydrogenase activity

EC:1.1.1.145, MetaCyc:1.1.1.145-RXN, Reactome:REACT_10031 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol, Homo sapiens", Reactome:REACT_10067 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one, Homo sapiens", Reactome:REACT_100839 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione, Danio rerio", Reactome:REACT_10090 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one, Homo sapiens", Reactome:REACT_10115 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one, Homo sapiens", Reactome:REACT_101983 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol, Bos taurus", Reactome:REACT_103390 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one, Bos taurus", Reactome:REACT_103657 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one, Sus scrofa", Reactome:REACT_103990 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one, Danio rerio", Reactome:REACT_104422 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione, Drosophila melanogaster", Reactome:REACT_104615 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one, Gallus gallus", Reactome:REACT_105565 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione, Mus musculus", Reactome:REACT_106120 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione, Bos taurus", Reactome:REACT_106214 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one, Danio rerio", Reactome:REACT_106644 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one, Taeniopygia guttata", Reactome:REACT_108035 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one, Canis familiaris", Reactome:REACT_108087 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one, Xenopus tropicalis", Reactome:REACT_108432 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol, Xenopus tropicalis", Reactome:REACT_109510 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one, Mus musculus", Reactome:REACT_111989 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol, Mycobacterium tuberculosis", Reactome:REACT_112248 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione, Escherichia coli", Reactome:REACT_113096 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione, Mycobacterium tuberculosis", Reactome:REACT_113257 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one, Escherichia coli", Reactome:REACT_113772 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one, Escherichia coli", Reactome:REACT_114424 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol, Escherichia coli", Reactome:REACT_114777 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one, Mycobacterium tuberculosis", Reactome:REACT_114921 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one, Mycobacterium tuberculosis", Reactome:REACT_115275 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one, Escherichia coli", Reactome:REACT_115303 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one, Mycobacterium tuberculosis", Reactome:REACT_28427 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one, Danio rerio", Reactome:REACT_28467 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one, Drosophila melanogaster", Reactome:REACT_29450 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol, Danio rerio", Reactome:REACT_30525 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one, Taeniopygia guttata", Reactome:REACT_30795 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione, Rattus norvegicus", Reactome:REACT_30899 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione, Canis familiaris", Reactome:REACT_32283 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione, Gallus gallus", Reactome:REACT_32783 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one, Mus musculus", Reactome:REACT_32924 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol, Gallus gallus", Reactome:REACT_33199 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one, Sus scrofa", Reactome:REACT_33352 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one, Gallus gallus", Reactome:REACT_34556 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one, Rattus norvegicus", Reactome:REACT_77900 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one, Drosophila melanogaster", Reactome:REACT_78893 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one, Xenopus tropicalis", Reactome:REACT_79104 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol, Sus scrofa", Reactome:REACT_79525 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one, Rattus norvegicus", Reactome:REACT_79553 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one, Bos taurus", Reactome:REACT_80359 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one, Drosophila melanogaster", Reactome:REACT_80746 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol, Rattus norvegicus", Reactome:REACT_81646 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one, Taeniopygia guttata", Reactome:REACT_82293 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one, Sus scrofa", Reactome:REACT_82688 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol, Mus musculus", Reactome:REACT_84251 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol, Canis familiaris", Reactome:REACT_85738 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one, Canis familiaris", Reactome:REACT_86717 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol, Drosophila melanogaster", Reactome:REACT_87612 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol, Taeniopygia guttata", Reactome:REACT_88118 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one, Mus musculus", Reactome:REACT_88292 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one, Rattus norvegicus", Reactome:REACT_88643 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one, Xenopus tropicalis", Reactome:REACT_91120 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one, Gallus gallus", Reactome:REACT_93787 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione, Taeniopygia guttata", Reactome:REACT_94450 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione, Xenopus tropicalis", Reactome:REACT_96507 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione, Sus scrofa", Reactome:REACT_99573 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one, Canis familiaris", Reactome:REACT_99689 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one, Bos taurus", Reactome:REACT_9989 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione, Homo sapiens"

3beta-HSDH