2-isopropylmalate synthase activity

Source:http://linkedlifedata.com/resource/geneontology/id/GO:0003852

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
skos:definition
"Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H(2)O = (2S)-2-isopropylmalate + CoA + H(+)." [EC:2.3.3.13, RHEA:21527]
skos:inScheme
skos:prefLabel
2-isopropylmalate synthase activity
skos:altLabel
3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating) activity, acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming), alpha-IPM synthetase activity, alpha-isopropylmalate synthase activity, alpha-isopropylmalate synthetase activity, alpha-isopropylmalic synthetase activity, isopropylmalate synthase activity, isopropylmalate synthetase activity
skos:notation
EC:2.3.3.13, KEGG:R01213, MetaCyc:2-ISOPROPYLMALATESYN-RXN, RHEA:21527
skos:note
Note that this function was formerly EC:4.1.3.12.
skos:broader