Source:http://linkedlifedata.com/resource/geneontology/id/GO:0002224
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"Any series of molecular signals generated as a consequence of binding to a toll-like receptor. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149, PMID:12467241, PMID:12524386, PMID:12855817, PMID:15585605, PMID:15728447]
|
| skos:inScheme | |
| skos:prefLabel |
toll-like receptor signaling pathway
|
| skos:altLabel |
TLR signaling pathway,
toll-like receptor signalling pathway
|
| skos:notation |
Reactome:REACT_25035 "Innate immune response mediated by toll like receptors, Gallus gallus"
|
| skos:note |
This term was added by GO_REF:0000022. Note that the vertebrate toll-like receptors, unlike the Drosophila Toll molecule, directly bind their ligands. The Drosophila Toll molecule requires the Sptzle factor to bind microbial ligands and then the receptor in order to initiate innate immune responses.
|
| skos:broader |