Statements in which the resource exists as a subject.
PredicateObject
rdf:type
skos:definition
"A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway." [http://www.peroxisome.org/Scientist/Biochemistry/alpha-oxidation.html]
skos:inScheme
skos:prefLabel
fatty acid alpha-oxidation
skos:notation
MetaCyc:PWY-2501, Reactome:REACT_103076 "Alpha-oxidation of phytanate, Dictyostelium discoideum", Reactome:REACT_106518 "Alpha-oxidation of phytanate, Drosophila melanogaster", Reactome:REACT_106956 "Alpha-oxidation of phytanate, Mus musculus", Reactome:REACT_107335 "Alpha-oxidation of phytanate, Taeniopygia guttata", Reactome:REACT_109097 "Alpha-oxidation of phytanate, Saccharomyces cerevisiae", Reactome:REACT_17003 "Alpha-oxidation of phytanate, Homo sapiens", Reactome:REACT_29885 "Alpha-oxidation of phytanate, Oryza sativa", Reactome:REACT_47735 "Alpha-oxidation of phytanate, Gallus gallus", Reactome:REACT_78088 "Alpha-oxidation of phytanate, Bos taurus", Reactome:REACT_81097 "Alpha-oxidation of phytanate, Xenopus tropicalis", Reactome:REACT_83317 "Alpha-oxidation of phytanate, Caenorhabditis elegans", Reactome:REACT_87622 "Alpha-oxidation of phytanate, Sus scrofa", Reactome:REACT_87835 "Alpha-oxidation of phytanate, Arabidopsis thaliana", Reactome:REACT_90750 "Alpha-oxidation of phytanate, Canis familiaris", Reactome:REACT_92361 "Alpha-oxidation of phytanate, Mycobacterium tuberculosis", Reactome:REACT_94726 "Alpha-oxidation of phytanate, Escherichia coli", Reactome:REACT_94872 "Alpha-oxidation of phytanate, Rattus norvegicus", Reactome:REACT_96409 "Alpha-oxidation of phytanate, Danio rerio", Reactome:REACT_98637 "Alpha-oxidation of phytanate, Schizosaccharomyces pombe"
skos:broader