Source:http://linkedlifedata.com/resource/geneontology/id/GO:0001105
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between activating transcription factors and the basal RNAP II transcription machinery." [GOC:txnOH, PMID:10213677, PMID:16858867]
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| skos:inScheme | |
| skos:prefLabel |
RNA polymerase II transcription coactivator activity
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| skos:altLabel |
RNA polymerase II transcription co-activator activity
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| skos:note |
Note that some basal transcription factors are themselves considered to have coactivator activity, in that they mediate interactions between an activator and either RNA polymerase II itself or another basal transcription factor.
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| skos:broader |