Source:http://linkedlifedata.com/resource/geneontology/id/GO:0000398
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced." [GOC:krc, ISBN:0198506732, ISBN:0879695897]
|
| skos:inScheme | |
| skos:prefLabel |
mRNA splicing, via spliceosome
|
| skos:altLabel |
nuclear mRNA splicing, via spliceosome
|
| skos:notation |
Reactome:REACT_101135 "mRNA Splicing - Minor Pathway, Drosophila melanogaster",
Reactome:REACT_101749 "mRNA Splicing - Minor Pathway, Caenorhabditis elegans",
Reactome:REACT_106268 "mRNA Splicing - Major Pathway, Gallus gallus",
Reactome:REACT_107907 "mRNA Splicing - Minor Pathway, Schizosaccharomyces pombe",
Reactome:REACT_109091 "mRNA Splicing - Minor Pathway, Rattus norvegicus",
Reactome:REACT_112200 "mRNA Splicing - Major Pathway, Arabidopsis thaliana",
Reactome:REACT_114266 "mRNA Splicing - Major Pathway, Oryza sativa",
Reactome:REACT_114738 "mRNA Splicing - Major Pathway, Taeniopygia guttata",
Reactome:REACT_1753 "mRNA Splicing - Minor Pathway, Homo sapiens",
Reactome:REACT_30984 "mRNA Splicing - Minor Pathway, Plasmodium falciparum",
Reactome:REACT_32449 "mRNA Splicing - Minor Pathway, Canis familiaris",
Reactome:REACT_34020 "mRNA Splicing - Minor Pathway, Dictyostelium discoideum",
Reactome:REACT_467 "mRNA Splicing - Major Pathway, Homo sapiens",
Reactome:REACT_81417 "mRNA Splicing - Major Pathway, Canis familiaris",
Reactome:REACT_82149 "mRNA Splicing - Minor Pathway, Danio rerio",
Reactome:REACT_85452 "mRNA Splicing - Major Pathway, Bos taurus",
Reactome:REACT_86489 "mRNA Splicing - Minor Pathway, Mus musculus",
Reactome:REACT_88186 "mRNA Splicing - Minor Pathway, Oryza sativa",
Reactome:REACT_89168 "mRNA Splicing - Minor Pathway, Gallus gallus",
Reactome:REACT_90296 "mRNA Splicing - Major Pathway, Danio rerio",
Reactome:REACT_91088 "mRNA Splicing - Minor Pathway, Arabidopsis thaliana",
Reactome:REACT_91611 "mRNA Splicing - Major Pathway, Drosophila melanogaster",
Reactome:REACT_91773 "mRNA Splicing - Minor Pathway, Bos taurus",
Reactome:REACT_93740 "mRNA Splicing - Major Pathway, Caenorhabditis elegans",
Reactome:REACT_93843 "mRNA Splicing - Major Pathway, Rattus norvegicus",
Reactome:REACT_95764 "mRNA Splicing - Major Pathway, Mus musculus",
Reactome:REACT_99123 "mRNA Splicing - Major Pathway, Xenopus tropicalis",
Reactome:REACT_99763 "mRNA Splicing - Minor Pathway, Xenopus tropicalis"
|
| skos:note |
Note that although the many U12-type introns have the sequence AT-AC at the intron termini, some introns with these terminal sequences are spliced by the U2-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron. Note that although the majority of U2-type introns have the sequence GU-AG at the intron termini, some introns with these terminal sequences are spliced by the U12-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron.
|
| skos:broader | |
| skos:relatedSynonym |
splicing AT-AC intron,
splicing GT-AG intron
|
| skos:narrowSynonym |
nuclear mRNA splicing via U12-type spliceosome,
nuclear mRNA splicing via U2-type spliceosome
|
| skos:broadSynonym |
mRNA splicing,
pre-mRNA splicing
|