Source:http://linkedlifedata.com/resource/entrezgene/interaction/6387-155971
| Predicate | Object |
|---|---|
| rdf:type | |
| entrezgene:pubmed |
pubmed-article:10430052,
pubmed-article:10486323,
pubmed-article:10582593,
pubmed-article:10600606,
pubmed-article:10820198,
pubmed-article:10872839,
pubmed-article:11162626,
pubmed-article:11287575,
pubmed-article:12482395,
pubmed-article:12787886,
pubmed-article:12834106,
pubmed-article:15113900,
pubmed-article:15710459,
pubmed-article:15748209,
pubmed-article:15972662,
pubmed-article:16188969,
pubmed-article:16343773,
pubmed-article:17507482,
pubmed-article:20181695,
pubmed-article:20817073,
pubmed-article:20835359,
pubmed-article:20929726,
pubmed-article:20967243,
pubmed-article:21459858,
pubmed-article:22101518,
pubmed-article:22473778,
pubmed-article:22954308,
pubmed-article:8976200,
pubmed-article:9601645,
pubmed-article:9653130,
pubmed-article:9744279,
pubmed-article:9826729
|
| entrezgene:interactant | |
| entrezgene:geneRifText |
A synthetic peptide domain of the V3 region of HIV-1 gp120 activates the FPRL1 receptor in monocytes and neutrophils and causes reduced response to several chemokines that use multiple cell receptors, including SDF-1alpha and RANTES,
Apoptosis of CD8+ T cells is mediated by the interaction between TNF-alpha bound to the membrane of macrophages (mbTNF) and a receptor on CD8+ T cells (TNF-receptor II, or TNFRII), which is upregulated by treatment with recombinant HIV-1 gp120 or SDF-1,
CXCL12 and HIV-1 gp120 modulate the excitability of Cajal-Retzius cells in opposite directions,
CXCL12 variant proteins exhibits the various levels of inhibition of HIV-1 X4 Env-mediated fusion. The strongest and weakest inhibition activities among the variant proteins in the X4 Env fusion assay are CXCL12gamma and CXCL12delta, respectively,
CXCR4-tropic and CXCR4/CCR5 dual-tropic HIV-1 gp120 proteins inhibit B cell chemotaxis toward CXCL12, CCL20, and CCL21, and gp120-induced p38 MAPK activation is triggered by CCL21 and CCL20,
Chemokines such as fractalkine, macrophage-derived chemokine (MDC), RANTES, and SDF-1alpha are able to block gp120-induced apoptosis of hippocampal neurons; both fractalkine and MDC activate ERK-1/2, while SDF-1alpha activates CREB,
HIV-1 gp120 abnormally interferes with SDF-1-mediated T cell chemotaxis and cell migration in resting CD4+ T Cells,
HIV-1 gp120 from a T-cell-tropic virus causes CD4-dependent antagonism of CXCR4 response to SDF-1alpha, whereas gp120 from macrophage-tropic viruses causes CD4-dependent antagonism of CCR5 response to MIP-1alpha,
RANTES, stromal derived factor-1alpha (SDF-1alpha), macrophage-derived chemokine (MDC), and their combination attenuate HIV-1 gp120-induced food and water intake decrease in rats,
SDF-1alpha reverses gp120-induced downregulation of CD79b in CD40- and IL-4-activated purified HIV-1 seronegative human peripheral blood B cells,
The ability of HIV-1 gp120 to inhibit SDF-1a-induced chemotaxis is mediated by the CD4 receptor and Lck signaling,
The death rate of CD8+ T cells by apoptosis, which is induced by HIV-1 gp120 from CXCR4-tropic HIV strains or by the ligand of the chemokine receptor CXCR4 (SDF-1), increased markedly during HIV infection of peripheral blood mononuclear cells,
The entry of T cell-tropic HIV-1 isolates into cells is blocked by SDF-1, which interacts with the HIV-1 gp120 coreceptor CXCR4,
The fusion of insulin-like growth factor I (IGF I) with stromal cell-derived factor I or alpha1 proteinase inhibitor has the capacity to compete with the binding of HIV-1 gp120 to CD4 receptor
|
| entrezgene:keyphrase |
inhibits,
interacts with,
inhibited by
|