Source:http://linkedlifedata.com/resource/entrezgene/interaction/6351-156110
| Predicate | Object |
|---|---|
| rdf:type | |
| entrezgene:pubmed | |
| entrezgene:interactant | |
| entrezgene:geneRifText |
A novel domain (K(92)EK) within Nef is required for Nef-dependent MIP-1beta production by infected macrophages,
HIV-1 Nef expression by immature human and macaque dendritic cells (DCs) upregulates IL-6, IL-12, TNF-alpha, CXCL8, CCL3, and CCL4 release, but without upregulating co-stimulatory and other molecules characteristic of mature DCs,
HIV-1 Nef induces the production of two CC-chemokines, macrophage inflammatory proteins 1alpha and 1beta, in HIV-1-infected macrophages,
HIV-1 Nef-pulsed iDCs downregulate MIP-1beta and RANTES expression in NK cells,
Secretion of MIP-1beta from Nef-specific CD8+ T cells is associated with nonprogressive HIV-1 infection
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| entrezgene:keyphrase |
downregulates,
interacts with,
upregulates
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